Investigating the cytotoxicity of platinum(II) complexes incorporating bidentate pyridyl-1,2,3-triazole “click” ligands

Simple item page
dc.contributor.authorPages, BJen_AU
dc.contributor.authorSakoff, Jen_AU
dc.contributor.authorGilbert, Jen_AU
dc.contributor.authorZhang, Yen_AU
dc.contributor.authorLi, Fen_AU
dc.contributor.authorPreston, Den_AU
dc.contributor.authorCrowley, JDen_AU
dc.contributor.authorAldrich-Wright, JRen_AU
dc.date.accessioned2020-02-13T05:33:09Zen_AU
dc.date.available2020-02-13T05:33:09Zen_AU
dc.date.issued2016-12-01en_AU
dc.date.statistics2019-11-12en_AU
dc.description.abstractSix platinum(II) complexes of the type [Pt(PL)(AL)]2 +, where PL is a bidentate pyridyl-1,2,3-triazole “click” ligand and AL is the R,R or S,S isomer of 1.2-diaminocyclohexane, have been synthesised and characterised by several methods including elemental microanalysis, proton NMR spectroscopy and X-ray crystallography. The in vitro cytotoxicity of each complex was assessed in eleven cell lines, revealing moderate to good activity for complexes incorporating 2-(1-phenyl-1H-1,2,3-triazol-4-yl)pyridine. © 2016 Elsevier B.V.en_AU
dc.identifier.citationPages, B. J., Sakoff, J., Gilbert, J., Zhang, Y., Li, F., Preston, D., Cowley, J. D., & Aldrich-Wright, J. R. (2016). Investigating the cytotoxicity of platinum (II) complexes incorporating bidentate pyridyl-1, 2, 3-triazole “click” ligands. Journal of Inorganic Biochemistry, 165, 92-99. doi:10.1016/j.jinorgbio.2016.06.017en_AU
dc.identifier.govdoc9012en_AU
dc.identifier.issn0162-0134en_AU
dc.identifier.journaltitleJournal of Inorganic Biochemistryen_AU
dc.identifier.pagination92-99en_AU
dc.identifier.urihttps://doi.org/10.1016/j.jinorgbio.2016.06.017en_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/9107en_AU
dc.identifier.volume165en_AU
dc.language.isoenen_AU
dc.publisherElsevier B.V.en_AU
dc.subjectPlatinumen_AU
dc.subjectTriazolesen_AU
dc.subjectGrowthen_AU
dc.subjectCrystal structureen_AU
dc.subjectCrystallographyen_AU
dc.subjectNuclear magnetic resonanceen_AU
dc.subjectSpectroscopyen_AU
dc.subjectPyridineen_AU
dc.subjectIn vitroen_AU
dc.subjectX-ray diffractionen_AU
dc.subjectLigandsen_AU
dc.titleInvestigating the cytotoxicity of platinum(II) complexes incorporating bidentate pyridyl-1,2,3-triazole “click” ligandsen_AU
dc.typeJournal Articleen_AU
Files
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal Articles