In vivo PET imaging with [18F]FDG to explain improved glucose uptake in an apolipoprotein A-I treated mouse model of diabetes
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Springer Nature
Abstract
Type 2 diabetes is characterised by decreased HDL levels, as well as the level of apolipoprotein A-I (apoA-I), the main apolipoprotein of HDLs. Pharmacological elevation of HDL and apoA-I levels is associated with improved glycaemic control in patients with type 2 diabetes. This is partly due to improved glucose uptake in skeletal muscle.© 2016 Springer Nature
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Cochran, B. J., Ryder, W. J., Parmar, A., Tang, S., Reilhac, A., Arthur, A., Charil, A., Hamze, H., Barter, P. J., Kritharides, L. Meikle, S. R., Grégoire, M. C. & Rye, K. (2016). In vivo PET imaging with [18F] FDG to explain improved glucose uptake in an apolipoprotein AI treated mouse model of diabetes. Diabetologia, 59(9), 1977-1984. doi:10.1007/s00125-016-3993-5