3D sensitive volume microdosimeter with improved tissue equivalency: charge collection study and its application in 12C ion therapy

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dc.contributor.authorJames, Ben_AU
dc.contributor.authorTran, LTen_AU
dc.contributor.authorBolst, Den_AU
dc.contributor.authorProkopovich, DAen_AU
dc.contributor.authorReinhard, MIen_AU
dc.contributor.authorLerch, MLFen_AU
dc.contributor.authorPetasecca, Men_AU
dc.contributor.authorGuatelli, Sen_AU
dc.contributor.authorPovoli, Men_AU
dc.contributor.authorKok, Aen_AU
dc.contributor.authorMatsufuji, Nen_AU
dc.contributor.authorJackson, Men_AU
dc.contributor.authorRosenfeld, ABen_AU
dc.date.accessioned2023-11-21T22:01:19Zen_AU
dc.date.available2023-11-21T22:01:19Zen_AU
dc.date.issued2018-02-06en_AU
dc.date.statistics2023-06-27en_AU
dc.description.abstractThis research focuses on the characterisation of a new 3D sensitive volume (SV) microdosimeter covered with polyimide – a material which closely mimics human tissue. The electrical and charge collection properties of the device were investigated and its application in 12C ion therapy were studied. Charge collection studies revealed uniform charge collection and no cross talk between adjacent SVs. To study the microdosimetric response in 12C ion therapy, the new polyimide mushroom microdosimeter were placed at various positions along the central axis of a 290 MeV/u 12C ion spread out Bragg peak (SOBP) at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. From these microdosimetric spectra, dose mean lineal energy $(\overline{{y}_{D})}$ and RBE10 results were obtained, with RBE10 increasing from 1.3 at the entrance to 2.7 at the end of the SOBP. The results obtained in this work show that the new generation of mushroom microdosimeters, covered with tissue equivalent polyimide material, are a useful tool for quality assurance in heavy ion therapy applications. © Open Access - CC BY - IOP Publishing Ltd.en_AU
dc.identifier.articlenumber012012en_AU
dc.identifier.citationJames, B., Tran, L. T., Bolst, D., Prokopovich, D., Reinhard, M., Lerch, M., Petasecca, M., Guatelli, S., Povoli, M., Kok, A., Matsufuji, N., Jackson, M., & Rosenfeld, A. (2019). 3D sensitive volume microdosimeter with improved tissue equivalency: charge collection study and its application in 12C ion therapy. Paper presented to the Mini-Micro and Nano Dosimetry and Innovative Technologies in Radiation Oncology, MMNDITRO 2018, 6–11 February 2018, Mooloolaba, Queensland, Australia. In Journal of Physics: Conference Series, 1154(1), 012012. doi:10.1088/1742-6596/1154/1/012012en_AU
dc.identifier.conferenceenddate2018-02-11en_AU
dc.identifier.conferencenameMini-Micro and Dosimetry and Innovative Technologies in Radiation Oncology, MMNDITRO 2018en_AU
dc.identifier.conferenceplaceMooloolaba, Queensland, Australiaen_AU
dc.identifier.conferencestartdate2018-02-06en_AU
dc.identifier.issue1en_AU
dc.identifier.journaltitleJournal of Physics: Conference Seriesen_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15221en_AU
dc.identifier.volume1154en_AU
dc.language.isoenen_AU
dc.publisherIOP Publishingen_AU
dc.relation.urihttps://iopscience.iop.org/article/10.1088/1742-6596/1154/1/012012/pdfen_AU
dc.subjectMicrodosimetryen_AU
dc.subjectAnimal tissuesen_AU
dc.subjectTherapyen_AU
dc.subjectBragg curveen_AU
dc.subjectMeetingsen_AU
dc.subjectElectrical propertiesen_AU
dc.title3D sensitive volume microdosimeter with improved tissue equivalency: charge collection study and its application in 12C ion therapyen_AU
dc.typeConference Abstracten_AU
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