Radium intestinal transfer studies
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Date
1989-09-22
Journal Title
Journal ISSN
Volume Title
Publisher
AINSE
Abstract
Previous work has shown that 226Ra ^s concentrated within the tissues of fresh water mussels in insoluble granules. It is present as an insoluble phosphate compound together with Ca, Mg, Ba, Fe and
Al. Because mussels form part of the traditional diet of Aboriginals, this work has been set up to measure the transfer rate of this radium-226 species as it is found in the mussel tissue, in comparison to radium as a simple chloride, across the gut wall of rats to gain comparative information for human dose rate calculations.
FEED TRIALS
Standard rat cages were adapted to allow separate faeces and urine collection, as well as a measured food dose. Freshwater mussels are obtained from the Northern Territory (supplied by the OSS). These are fed with algae and a radium-22 6 dose is added daily, after which the mussel tissue is removed from the shell, dried and blended to obtain a powder of even particle size. Pelleted laboratory animal feed (Milling Industries LTD), for which a content analysis from the company has been obtained, was blended and sieved to produce a powder of even particle size.
Feed trials using the above two ingredients were commenced in February 1987 and results have been obtained for 1, 14, 28, and 56 days dosage of female juvenile rats (4 weeks old) and female adult
rats (12 weeks and over).
Radium as the chloride has been incorporated into the standard laboratory rat food and a gut transfer rate obtained for juvenile and adult female rats for a seven day feed period.
Description
Physical copy held by ANSTO Library at DDC: 571.45/14
Keywords
Food chains, Ingestion, Intestinal Absorption, Molluscs, Radiation doses, Radionuclide kinetics, Radium 226, Rats, Vertebrates, Years living radioisotopes
Citation
Domel, R. U., & Beal, A. M. (1989). Radium intestinal transfer studies. Presentation to the 12th AINSE Radiation Biology Conference, 22-24th September 1989, Lucas Heights, (pp. 19). Lucas Heights, New South Wales : AINSE.