BioSAXS: the future of solution scattering at the Australian Synchrotron
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Date
2021-11-25
Journal Title
Journal ISSN
Volume Title
Publisher
Australian Nuclear Science and Technology Organisation
Abstract
BioSAXS is one of the new beamlines to be constructed at the Australian Synchrotron within the BRIGHT
program. The beamline is currently under construction and it is scheduled to phase into user operations in
mid-late 2022. BioSAXS will be a high-flux (~5 x 1014 ph/sec) small angle X-ray scattering beamline dedicated
to all sorts of solution scattering including dispersions, gels and soft matter, covering a variety of disciplines
from biology to chemistry and material sciences. The high flux of the beamline will provide enhanced data
quality and kinetic resolution, allowing for time-resolved studies on the millisecond timescale, as well as the
measurement of weak scatterers and low concentrations that wouldn’t otherwise be possible to measure. The
in-vacuum detector system at the end station will provide quick and highly automated camera changes, a q
range of ~0.0015 – 3 Å-1 and low background in collected data. The CoFlow, a pioneering development of the
Australian Synchrotron, will be the primary autoloading device for high throughput experiments. Other sample
environment options will include a stopped-flow and rheometer, temperature-controlled capillary stages,
a shear cell as well as a versatile magnetic-array system, optimized for experiments on magnetic nanoparticles
used in biomedical applications. The beamline’s sample platform will also accommodate the installation of
user equipment. The objective of this presentation is to demonstrate BioSAXS’ final design and capabilities
that will allow it to develop into a highly-automated and versatile beamline that can accommodate a widerange
of solution scattering experiments, complementing the existing SAXS/WAXS beamline to ensure the
world-leading capabilities of the SAXS offering at the Australian Synchrotron. © The Authors
Description
Keywords
Scattering, ANSTO, Australia, Australian organisations, Measuring instruments, Research programs
Citation
Kamma-Lorger, C., Venkatesan., S., Conesa-Zamora, G., Barnsley, L., Clulow, A., Jensen, B., Hamedi, N., Samardzic-Boban, V., & Roy, C. (2021). BioSAXS: the future of solution scattering at the Australian Synchrotron. Presentation to the ANSTO User Meeting, 24-26 November 2021, Online. Retrieved from:https://events01.synchrotron.org.au/event/146/contributions/4316/contribution.pdf