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Title: Sol-gel microspheres and nanospheres for controlled release applications
Other Titles: France-Australia symposium on nuclear medicine
Authors: Barbé, C
Beyer, R
Kong, L
Blackford, MG
Trautman, RL
Bartlett, JR
Keywords: Ceramics
Sol-gel process
Ambient temperature
Issue Date: 29-Apr-2002
Publisher: Australian Nuclear Science and Technology Organisation
Citation: Barbé, C., Beyer, R., Kong, L., Blackford, M., Trautman, R., & Bartlett, J. (2002). Sol-gel microspheres and nanospheres for controlled release applications. Poster 7 presented at the France-Australia Symposium on Nuclear Medicine : Methodology, Clinical Applications and Pharmacology. Volume of proceedings, Monday 29th April 2002, Sheraton on the Park Sydney, Australia.
Abstract: We present a novel approach to the synthesis of inorganic sol-gel microspheres for encapsulating organic and bioactive molecules, and controlling their subsequent release kinetics.The bioactive species are incorporated, at ambient temperature, into the inorganic particles using an emulsion gelation process, Independent control of the release rate (by adapting the nanostructure of the internal pore network to the physico-chemical properties of the bioactive molecules) and particle size (by tailoring the emulsion chemistry) is demonstrated.
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