Sol-gel microspheres and nanospheres for controlled release applications

We present a novel approach to the synthesis of inorganic sol-gel microspheres for encapsulating organic and bioactive molecules, and controlling their subsequent release kinetics.The bioactive species are incorporated, at ambient temperature, into the inorganic particles using an emulsion gelation process, Independent control of the release rate (by adapting the nanostructure of the internal pore network to the physico-chemical properties of the bioactive molecules) and particle size (by tailoring the emulsion chemistry) is demonstrated.

Keywords

Ceramics, Encapsulation, Gels, Sol-gel process, Microspheres, Ambient temperature, Emulsions, Chemistry

Citation

Barbé, C., Beyer, R., Kong, L., Blackford, M., Trautmann, R., & Bartlett, J. (2002). Sol-gel microspheres and nanospheres for controlled release applications. Poster presented to the France-Australia Symposium on nuclear medicine : methodology, clinical applications and pharmacology : volume of proceedings, Sheraton on the Park, Sydney, Australia, Monday 29th April 2002. Lucas Heights, NSW : Australian Nuclear Science and Technology Organisation, (pp. 59-60).

URI

https://apo.ansto.gov.au/dspace/handle/10238/10034

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