Efficient access to chromeno[4,3-b]quinolines related to dependensin

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Date
2017-08-08
Journal Title
Journal ISSN
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Publisher
© Georg Thieme Verlag Stuttgart
Abstract
We report a robust synthesis of novel chromeno[4,3-b]quinoline derivatives structurally similar to the natural product dependensin. The target compounds are accessed through the acid-catalysed condensation of 2-aminoacetophenones or 2-aminochalcones with substituted flavanones, which are in turn obtained from 2-hydroxyacetophenones and benzaldehydes. © 2017 Georg Thieme Verlag Stuttgart
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Keywords
Quinolines, Synthesis, Benzaldehyde, Dehydrocyclization, Molecules, Flavonoids
Citation
Dobrowolski, J. C., Fraser, B. H., Bhadbhade, M., Black, D. S., & Kumar, N. (2017). Efficient access to chromeno[4,3-b]quinolines related to dependensin. Synlett, 28(15), 1979-1983. doi:10.1055/s-0036-1589087
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