Itrax micro x-ray fluorescence (µXRF) for soft biological tissues
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Date
2018-10-06
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Determination of the elemental composition of soft biological tissue is a time-consuming and tedious process when using traditional analytical techniques. In this method, micro X-ray fluorescence (µXRF) via Itrax, a scanning instrument, was used to determine elemental abundance at a resolution of 200?µm. Itrax µXRF was initially designed for elemental profiling of geological cores, and the capability of this technique was extended to soft biological tissue samples. The samples were dried and ground into a fine powder before analysis. The scanner generates elemental values as counts per 1?mm and these values are standardised to obtain the relative elemental abundance of the elements present in the samples. The acquired data can be used for environmental and biological research.
• No literature could be found whereby the capability of Itrax µXRF has been extended to soft biological tissue samples.
• The major advantages Itrax has over conventional methods is that it is a simultaneous technique which allows data to be acquired for over 30 elements at once with minimal sample preparation.
• It is a non-destructive process where the samples can be re-used for additional analyses if necessary; this is especially useful when there is only a limited amount of sample available for other analyses. © 2018 Crown Copyright. Published by Elsevier B.V. This is an open access article under the CCBY license 4.0.
Description
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords
X-ray fluorescence analysis, Bioassay, Seafood, Food, Nondestructive analysis, Statistical models
Citation
Gadd, P., Gopi, K., Sammut, J., Saintilan, N., Crawford, J., & Mazumder, D. (2018). Itrax micro x-ray fluorescence (μXRF) for soft biological tissues. MethodsX, 5, 1267-1271. doi:10.1016/j.mex.2018.10.001