The high performance macromolecular crystallography (MX3) beamline

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dc.contributor.authorEriksson, Den_AU
dc.contributor.authorCaradoc-Davies, Ten_AU
dc.contributor.authorMagoulas, Cen_AU
dc.contributor.authorWong, Den_AU
dc.contributor.authorHarnandez Vivanco, Fen_AU
dc.contributor.authorCherukuvada, Hen_AU
dc.contributor.authorCain, Nen_AU
dc.contributor.authorRostan, Ren_AU
dc.contributor.authorNuthalapati, Sen_AU
dc.date.accessioned2023-12-08T06:29:38Zen_AU
dc.date.available2023-12-08T06:29:38Zen_AU
dc.date.issued2021-11-26en_AU
dc.date.statistics2023-04-26en_AU
dc.description.abstractThe MX3 beamline will extend the capabilities of the existing suite of MX beamlines at the Australian Synchrotron. It will allow collection on crystals that are too small or weakly diffracting for the current beamlines. A high level of automation will transform membrane protein micro crystal collection and high throughput projects such as drug and fragment screening. Sample positioning will be provided via an MD3-UP goniometer and an ISARA robot will allow 6 second sample exchange. Serial crystallography capability will be provided using in-tray screening and collection and fixed target silicon chip scanning stages. A dedicated cluster will provide real-time data processing and automated data collection will be standard. This will include automated location of crystals from a rastered volume with subsequent data collection on each crystal with resulting automated data merging from multiple crystals. Some outstanding questions for the user community relate to time-resolved crystallography, and injector experiment capabilities; options will be presented and discussed. © 2021 The Authorsen_AU
dc.identifier.citationEriksson, D., Caradoc-Davies, T., Magoulas, C., Wong, D., Harnandez Vivanco, F., Cherukuvada, H., Cain, N., Rostan, R., & Nuthalapati, S. (2021). The high performance macromolecular crystallography (MX3) beamline. Presentation to the ANSTO User Meeting, 24-26 November 2021, Online. Retrieved from: https://events01.synchrotron.org.au/event/146/contributions/4378/contribution.pdfen_AU
dc.identifier.conferenceenddate2021-11-26en_AU
dc.identifier.conferencenameANSTO User Meeting, 24-26 November 2021,en_AU
dc.identifier.conferenceplaceOnlineen_AU
dc.identifier.conferencestartdate2021-11-24en_AU
dc.identifier.urihttps://events01.synchrotron.org.au/event/146/contributions/4378/contribution.pdfen_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15280en_AU
dc.language.isoenen_AU
dc.publisherAustralian Nuclear Science and Technology Organisationen_AU
dc.subjectCrystallographyen_AU
dc.subjectBeamsen_AU
dc.subjectANSTOen_AU
dc.subjectAustralian organizationsen_AU
dc.subjectProteinsen_AU
dc.subjectCrystalsen_AU
dc.subjectSiliconen_AU
dc.subjectDataen_AU
dc.subjectMeasuring instrumentsen_AU
dc.titleThe high performance macromolecular crystallography (MX3) beamlineen_AU
dc.typeConference Presentationen_AU
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