Selenium speciation influences bioaccumulation in Limnodynastes peronii tadpoles

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dc.contributor.authorLanctôt, CMen_AU
dc.contributor.authorMelvin, SDen_AU
dc.contributor.authorCresswell, Ten_AU
dc.date.accessioned2021-12-22T19:45:32Zen_AU
dc.date.available2021-12-22T19:45:32Zen_AU
dc.date.issued2017-06en_AU
dc.date.statistics2021-11-22en_AU
dc.description.abstractDespite being essential for animal health and fitness, Se has a relatively narrow range between deficiency and toxicity, and excess Se can cause a variety of adverse effects in aquatic organisms. Amphibians are particularly vulnerable to contaminants during larval aquatic life stage, because they can accumulate toxic ions through various routes including skin, gills, lungs and digestive tract. Few attempts have been made to understand the tissue-specific accumulation of trace elements, including the impacts of chemical speciation in developing amphibian larvae. We used radiolabelled 75Se to explore the biokinetics and tissue distributions of the two dominant forms occurring in surface waters, selenite (SeIV) and selenate (SeVI). Tadpoles of the native Australian frog Limnodynastes peronii were exposed to Se in both forms, and live-animal gamma spectroscopy was used to track accumulation and retention over time. Tissue biodistributions were also quantified at the end of the uptake and depuration phases. Results showed the bioconcentration of SeIV to be 3 times greater compared to SeVI, but rates of elimination were similar for both forms. This suggests a change of Se speciation within the organism prior to excretion. Depuration kinetics were best described by a one-phase exponential decay model, and tadpoles retained approximately 19% of the accumulated Se after 12 days of depuration in clean water. Selenium bioaccumulation was greatest in digestive and excretory organs, as well as the eye, which may directly relate to previously reported Se-induced impairments. Results demonstrate how the use of radiotracing techniques can significantly improve our understanding of trace element toxicokinetics and tissue distributions in developing amphibians. From an environmental monitoring perspective, the findings highlight the importance of considering chemical speciation as this could influence the accuracy of risk assessment. Crown Copyright © 2017 Published by Elsevier B.V.en_AU
dc.description.sponsorshipAustralian Institute for Nuclear Science and Engineering (AINSE) Research Award (No. ALNGRA16029)en_AU
dc.identifier.citationLanctôt, C. M., Melvin, S. D., & Cresswell, T. (2017). Selenium speciation influences bioaccumulation in Limnodynastes peronii tadpoles. Aquatic Toxicology, 187, 1-8. doi:10.1016/j.aquatox.2017.03.009en_AU
dc.identifier.issn0166-445Xen_AU
dc.identifier.journaltitleAquatic Toxicologyen_AU
dc.identifier.pagination1-8en_AU
dc.identifier.urihttps://doi.org/10.1016/j.aquatox.2017.03.009en_AU
dc.identifier.urihttps://apo.ansto.gov.au/dspace/handle/10238/12640en_AU
dc.identifier.volume187en_AU
dc.language.isoenen_AU
dc.publisherElsevieren_AU
dc.subjectTracer techniquesen_AU
dc.subjectSeleniumen_AU
dc.subjectSelenium compoundsen_AU
dc.subjectSelenatesen_AU
dc.subjectSelenitesen_AU
dc.subjectAquatic organismsen_AU
dc.subjectAmphibiansen_AU
dc.subjectFrogsen_AU
dc.subjectBiological accumulationen_AU
dc.titleSelenium speciation influences bioaccumulation in Limnodynastes peronii tadpolesen_AU
dc.typeJournal Articleen_AU
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