Hybrid non-rigid registration method for registering rat skeletons from micro-CT images

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dc.contributor.authorXiao, Den_AU
dc.contributor.authorZahra, Den_AU
dc.contributor.authorBourgeat, Pen_AU
dc.contributor.authorTamayo, OAen_AU
dc.contributor.authorBerghofer, PJen_AU
dc.contributor.authorFripp, Jen_AU
dc.contributor.authorGrégoire, MCen_AU
dc.contributor.authorSalvado, Oen_AU
dc.date.accessioned2020-05-26T05:42:43Zen_AU
dc.date.available2020-05-26T05:42:43Zen_AU
dc.date.issued2009-05en_AU
dc.date.statistics2020-05-15en_AU
dc.description.abstractObjectives: A hybrid non-rigid registration method for automatic rat spine detection and registration and further rat limbs registration was proposed. Methods: We first developed an automatic algorithm to extract the rat spine from its whole-body skeleton and then detect top point on the spinous process of each vertebra starting from the first vertebra at thoracic vertebrae towards the tail. The extracted points were matched to the predefined corresponding points of the spine in a rat atlas. Their correspondences field was used to perform skeletons registration by thin-plate-spline (TPS). Further, we extend 3D shape context algorithm for landmarks matching for rat limbs between the atlas and the newly extracted skeletons. The correspondences found were used to perform the rat limb skeletons registration by TPS. Results: Experiments were described using phantoms and actual rat skeletons. Mean square errors decrease was observed during registration process. Visually, the skeletons were successfully registered. Conclusions: The method can improve the robustness of rat skeleton registration, even in the case of large variation in some postures and this first step work can be extended to further improve rat organs registration guided by the correspondences found from the skeletons.© 2009 by Society of Nuclear Medicineen_AU
dc.identifier.citationXiao, D., Zahra, D., Bourgeat, P., Tamayo, A. O., Berghofer, P., Fripp, J., Grégoire, M., & Salvado, O. (2009). Hybrid non-rigid registration method for registering rat skeletons from micro-CT images. Journal of Nuclear Medicine. 50(Supplement 2), 1428. en_AU
dc.identifier.govdoc9525en_AU
dc.identifier.issn2159-662Xen_AU
dc.identifier.issueSupplement 2en_AU
dc.identifier.journaltitleJournal of Nuclear Medicineen_AU
dc.identifier.pagination1428en_AU
dc.identifier.urihttps://jnm.snmjournals.org/content/50/supplement_2/1428en_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/9491en_AU
dc.identifier.volume50en_AU
dc.language.isoenen_AU
dc.publisherSociety of Nuclear Medicine and Molecular Imagingen_AU
dc.subjectRatsen_AU
dc.subjectCAT scanningen_AU
dc.subjectAlgorithmsen_AU
dc.subjectSkeletonen_AU
dc.subjectVertebraeen_AU
dc.subjectOrgansen_AU
dc.titleHybrid non-rigid registration method for registering rat skeletons from micro-CT imagesen_AU
dc.typeJournal articleen_AU
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