Assessment of a fast generated analytical matrix for rotating slat collimation iterative reconstruction: a possible method to optimize the collimation profile

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dc.contributor.authorBoisson, Fen_AU
dc.contributor.authorBekaert, Ven_AU
dc.contributor.authorReilhac, Aen_AU
dc.contributor.authorWurtz, Jen_AU
dc.contributor.authorBrasse, Den_AU
dc.date.accessioned2017-05-10T01:58:42Zen_AU
dc.date.available2017-05-10T01:58:42Zen_AU
dc.date.issued2015-02-26en_AU
dc.date.statistics2017-05-10en_AU
dc.description.abstractA polystyrene film spun onto polished silicon substrates was implanted with argon ions using plasma immersion ion implantation (PIII) to activate its surface for single-step immobilization of biological molecules. The film was subsequently investigated by X-ray and neutron reflectometry, ultraviolet (UV)–visible (vis) and Fourier transform infrared (FTIR) ellipsometry, FTIR and Raman spectroscopy, as well as nuclear reaction analysis to determine the structural and compositional transformations associated with the surface activation. The ion irradiation resulted in a significant densification of the carbon structure, which was accompanied by hydrogen loss. The density and hydrogen profiles in the modified surface layers were found to agree with the expected depths of ion implantation as calculated by the Stopping and Range of Ions in Matter (SRIM) software. The data demonstrate that the reduction in film thickness is due to ion-induced densification rather than the removal of material by etching. Characterization by FTIR, atomic force microscopy (AFM), ellipsometry, and X-ray reflectometry shows that polystyrene films modified in this way immobilize dense layers of protein (tropoelastin) directly from solution. A substantial fraction of the immobilized protein layer remains after rigorous washing with sodium dodecyl sulfate solution, indicating that its immobilization is by covalent bonding. © Copyright 2020 IOP Publishingen_AU
dc.identifier.citationBoisson, F., Bekaert, V., Reilhac, A., Wurtz, J., & Brasse, D. (2015). Assessment of a fast generated analytical matrix for rotating slat collimation iterative reconstruction: a possible method to optimize the collimation profile. Physics in Medicine and Biology, 60(6), 2403-2419. doi:10.1088/0031-9155/60/6/2403en_AU
dc.identifier.govdoc8185en_AU
dc.identifier.issn1361-6560en_AU
dc.identifier.issue6en_AU
dc.identifier.journaltitlePhysics in Medicine and Biologyen_AU
dc.identifier.pagination2403-2419en_AU
dc.identifier.urihttp://dx.doi.org/10.1088/0031-9155/60/6/2403en_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/8689en_AU
dc.identifier.volume60en_AU
dc.language.isoenen_AU
dc.publisherIOP Scienceen_AU
dc.subjectVisible radiationen_AU
dc.subjectPolystyreneen_AU
dc.subjectDataen_AU
dc.subjectBiological modelsen_AU
dc.subjectNeutron reflectorsen_AU
dc.subjectCarbon sourcesen_AU
dc.titleAssessment of a fast generated analytical matrix for rotating slat collimation iterative reconstruction: a possible method to optimize the collimation profileen_AU
dc.typeJournal Articleen_AU
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