Microfluidics in Planar Microchannels: Synthesis of Chemical Compounds On-Chip.

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dc.contributor.authorArima, Ven_AU
dc.contributor.authorWatts, Pen_AU
dc.contributor.authorPascali, Gen_AU
dc.date.accessioned2017-04-03T06:41:18Zen_AU
dc.date.available2017-04-03T06:41:18Zen_AU
dc.date.issued2014-10-14en_AU
dc.date.statistics2017-04-03en_AU
dc.description.abstractMicroreactors are a wide class of devices that are currently playing a prominent role in several research fields such as biology, medicine, food chemistry, environmental analysis, up to the production of compounds in organic chemistry. Several typologies of microreactors have been produced with tubular or planar shapes, of different materials and designs. In this chapter, an overview of planar microchannel-based microreactors and their application to organic chemistry is given. Initially, after recalling the main theoretical parameters of microfluidics, an introduction of the proposed technology and the main requirements to perform mixing, which is essential to perform chemical synthesis on-chip, is presented. Silicon and glass microreactors, the most common planar systems for organic chemistry, are described with the aim of pointing out the most important parameters to be taken into consideration in the planning of a specific microreactor to be used for mixing, purification or crystallization of chemicals at the microscale. Then, several applications of initially described microreactors to organic chemistry for research applications are given. In the next section, the use of planar microchannel microreactors in the field of radiochemistry is reported. The radiopharmaceutical application is not casual, being a sector in which the microreactor technology is very promising, due to the need of quickly producing small and fresh amounts of products in a controlled environment. Finally, for completeness, other approaches beyond planar microchannels are mentioned: mesoreactors towards industrial level synthesis and micro-vessels for radiochemistry. © Springer International Publishing Switzerland 2015en_AU
dc.identifier.booktitleLab-on-a-Chip Devices and Micro-Total Analysis Systems: A Practical Guideen_AU
dc.identifier.citationArima, V., Watts, P., & Pascali, G. (2015). Microfluidics in planar microchannels: synthesis of chemical compounds on-chip. In J. Castillo-León & E. W. Svendsen (Eds.), Lab-on-a-Chip Devices and Micro-Total Analysis Systems: A Practical Guide (pp. 197-239). New York: Springer International Publishing.en_AU
dc.identifier.editorsJ. Castillo-Le�n & E. W. Svendsenen_AU
dc.identifier.govdoc8069en_AU
dc.identifier.isbn978-3-319-08686-6en_AU
dc.identifier.pagination197-239en_AU
dc.identifier.placeofpublicationNew York. USAen_AU
dc.identifier.urihttps://doi.org/10.1007/978-3-319-08687-3_8en_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/8525en_AU
dc.language.isoenen_AU
dc.publisherSpringer Linken_AU
dc.subjectSynthesisen_AU
dc.subjectSiliconen_AU
dc.subjectGlassen_AU
dc.subjectPurificationen_AU
dc.subjectCrystallizationen_AU
dc.subjectRadiochemistryen_AU
dc.titleMicrofluidics in Planar Microchannels: Synthesis of Chemical Compounds On-Chip.en_AU
dc.typeBook chapteren_AU
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