Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?
No Thumbnail Available
Date
2013-07-01
Journal Title
Journal ISSN
Volume Title
Publisher
John Wiley and Sons Inc.
Abstract
Posttraumatic epilepsy (PTE) occurs in a proportion of traumatic brain injury (TBI) cases, significantly compounding the disability, and risk of injury and death for sufferers. To date, predictive biomarkers for PTE have not been identified. This study used the lateral fluid percussion injury (LFPI) rat model of TBI to investigate whether structural, functional, and behavioral changes post‐TBI relate to the later development of PTE. © 2013 International League Against Epilepsy
Description
Keywords
Epilepsy, Fluorine 18, Injuries, Nuclear magnetic resonance, Electroencephalography, Radiopharmaceuticals
Citation
Shultz, S. R., Cardamone, L., Liu, Y. R., Hogan, R. E., Maccotta, L., Wright, D. K., Sheng, O., Koe, A., Grégoire, M. C., Williams, J. P. Hicks, R. J., Jones, N. C., Myers, D. E., O'Brien, T. J., & Bouillered, V. (2013). Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?. Epilepsia, 54(7), 1240-1250. doi:10.1111/epi.12223