Temperature- and pH-responsive micelles with collapsible poly(N-isopropylacrylamide) headgroups

Simple item page
dc.contributor.authorFitzGerald, PAen_AU
dc.contributor.authorGupta, Sen_AU
dc.contributor.authorWood, Ken_AU
dc.contributor.authorPerrier, Sen_AU
dc.contributor.authorWarr, GGen_AU
dc.date.accessioned2016-08-11T23:06:27Zen_AU
dc.date.available2016-08-11T23:06:27Zen_AU
dc.date.issued2014-06-18en_AU
dc.date.statistics2016-08-12en_AU
dc.description.abstractWe have studied the micelle formation and phase behavior of a series of temperature- and pH-responsive surfactants prepared by controlled radical (RAFT) polymerization. These C12NIPAMm surfactants consist of a dodecyl tail, a poly(N-isopropylacrylamide) (polyNIPAM) headgroup with average degrees of polymerization of between 7 and 96, and an ionizable carboxylate group. In the un-ionized state, these surfactants phase separate on warming toward a lower critical solution temperature (LCST), which decreases as the length of the NIPAM group is decreased. This is in agreement with the behavior of conventional nonionic poly(ethylene oxide)-based surfactants but is very different from that of polyNIPAM oligomer solutions. Small angle neutron scattering (SANS) shows that these surfactants self-assemble into micelles consisting of a nearly spherical hydrophobic core surrounded by a “hairy” polyNIPAM shell far below their LCST. Upon warming, the micelles undergo a sphere-to-rod transition induced by the collapse of the polyNIPAM shell, causing a reduction in the headgroup area. In the un-ionized state the demixing follows at the LCST, but a single charge on the free polymer end completely suppresses phase separation, allowing micelles to undergo a shape change but remain dissolved. © 2014, American Chemical Society.en_AU
dc.identifier.citationFitzGerald, P. A., Gupta, S., Wood, K., Perrier, S., & Warr, G. G. (2014). Temperature- and pH-responsive micelles with collapsible poly(N-isopropylacrylamide) headgroups. Langmuir, 30(27), 7986-7992. doi:10.1021/la501861ten_AU
dc.identifier.govdoc6919en_AU
dc.identifier.issn1520-5827en_AU
dc.identifier.issue27en_AU
dc.identifier.journaltitleLangmuiren_AU
dc.identifier.pagination7986-7992en_AU
dc.identifier.urihttp://dx.doi.org/10.1021/la501861ten_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/7277en_AU
dc.identifier.volume30en_AU
dc.language.isoenen_AU
dc.publisherACS Publicationsen_AU
dc.subjectPolymerizationen_AU
dc.subjectCarboxylationen_AU
dc.subjectMicellar systemsen_AU
dc.subjectTemperature rangeen_AU
dc.subjectMoleculesen_AU
dc.titleTemperature- and pH-responsive micelles with collapsible poly(N-isopropylacrylamide) headgroupsen_AU
dc.typeJournal Articleen_AU
Files
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal Articles