Synthesis of per-deuterated alkyl amines for the preparation of deuterated organic pyromellitamide gelators

Yepuri, NR; Jamieson, SA; Darwish, TA; Rawal, A; Hook, JM; Thordarson, P; Holden, PJ; James, M

Synthesis of per-deuterated alkyl amines for the preparation of deuterated organic pyromellitamide gelators

Date

2013-05-15

Authors

Publisher

Pergamon-Elsevier Science Ltd

Abstract

A general, direct and scalable synthesis of per-deuterated alkyl amines is reported, together with their incorporation into pyromellitamides, which form self-assembled gels in cyclohexane. The deuterium labelling of these gelators allows the study of the dynamic intermolecular interactions in these materials using solid-state 2H NMR spectroscopy.© 2013, Elsevier Ltd.

Keywords

Neutron reflectors, Platinum, Amines, Gels, Drugs, Films

Citation

Yepuri, N. R., Jamieson, S. A., Darwish, T. A., Rawal, A., Hook, J. M., Thordarson, P., Holden, P. J., & James, M. (2013). Synthesis of per-deuterated alkyl amines for the preparation of deuterated organic pyromellitamide gelators. Tetrahedron Letters, 54, 2538-2541. doi:10.1016/j.tetlet.2013.03.031