Ultraviolet light transmission through the human corneal stroma is reduced in the periphery

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dc.contributor.authorDoutch, JJen_AU
dc.contributor.authorQuantock, AJen_AU
dc.contributor.authorJoyce, NCen_AU
dc.contributor.authorMeek, KMen_AU
dc.date.accessioned2012-06-18T03:36:27Zen_AU
dc.date.available2012-06-18T03:36:27Zen_AU
dc.date.issued2012-03-21en_AU
dc.date.statistics2012-06-18en_AU
dc.description.abstractThis article investigates in vitro light transmission through the human cornea in the ultraviolet (UV) portion of the electromagnetic spectrum as a function of position across the cornea from center to periphery. Spectrophotometry was used to measure UV transmission in the wavelength range 310-400 nm, from the central cornea to its periphery. UV transmission decreases away from the center, and this is attributed to scattering and absorbance. Corneal endothelial cells, which line the back of the cornea and are more numerous in the periphery, therefore receive a lower dose of UV than do those in the central cornea. This is consistent with the recent observation that endothelial cells in the corneal periphery exhibit less nuclear oxidative DNA damage than those in the central cornea. © 2012, Cell Press.en_AU
dc.identifier.citationDoutch, J. J., Quantock, A. J., Joyce, N. C., Meek, K. M. (2012). Ultraviolet Light Transmission through the Human Corneal Stroma Is Reduced in the Periphery. Biophysical Journal, 102(6), 1258-1264. doi:10.1016/j.bpj.2012.02.023en_AU
dc.identifier.govdoc4307en_AU
dc.identifier.issn0006-3495en_AU
dc.identifier.issue6en_AU
dc.identifier.journaltitleBiophysical Journalen_AU
dc.identifier.pagination1258-1264en_AU
dc.identifier.urihttp://dx.doi.org/10.1016/j.bpj.2012.02.023en_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/4340en_AU
dc.identifier.volume102en_AU
dc.language.isoenen_AU
dc.publisherCell Pressen_AU
dc.subjectHydrationen_AU
dc.subjectCollagenen_AU
dc.subjectEndotheliumen_AU
dc.subjectCorneaen_AU
dc.subjectOpacityen_AU
dc.subjectScatteringen_AU
dc.titleUltraviolet light transmission through the human corneal stroma is reduced in the peripheryen_AU
dc.typeJournal Articleen_AU
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