Positrons as imaging agents and probes in nanotechnology.

Simple item page
dc.contributor.authorSmith, SVen_AU
dc.date.accessioned2010-10-18T05:48:26Zen_AU
dc.date.available2010-10-18T05:48:26Zen_AU
dc.date.issued2008-11-24en_AU
dc.date.statistics2008-11-24en_AU
dc.description.abstractPositron emission tomography (PET) tracks a positron emitting radiopharmaceutical injected into the body and generates a 3-dimensional image of its location. Introduced in the early 70s, it has now developed into a powerful medical diagnostic tool for routine clinical use as well as in drug development. Unrivalled as a highly sensitive, specific and non-invasive imaging tool, PET unfortunately lacks the resolution of Computer Tomography (CT) and Magnetic Resonance Imaging (MRI). As the resolution of PET depends significantly on the energy of the positron incorporated in the radiopharmaceutical and its interaction with its surrounding tissue, there is growing interest in expanding our understanding of how positrons interact at the atomic and molecular level. A better understanding of these interactions will contribute to improving the resolution of PET and assist in the design of better imaging agents. Positrons are also used in Positron Annihilation Lifetime Spectroscopy (PALS) to determine electron density and or presence and incidence of micro- and mesopores (0.1 to 10 nm) in materials. The control of porosity in engineered materials is crucial for applications such as controlled release or air and water resistant films. Equally important to the design of nano and microtechnologies, is our understanding of the microenvironments within these pores and on surfaces. Hence as radiopharmaceuticals are designed to track disease, nuclear probes (radioactive molecules) are synthesized to investigate the chemical properties within these pores. This article will give a brief overview of the present role of positrons in imaging as well as explore its potential to contribute in the engineering of new materials to the marketplace. © 2020 IOP Publishingen_AU
dc.identifier.articlenumber12044en_AU
dc.identifier.citationSmith, S. V. (2008). Positrons as imaging agents and probes in nanotechnology. Paper presented to The 8th Asian International Seminar on Atomic and Molecular Physics, 24th - 28th November 2008. University of Western Australia: Perth, Australia. In Journal of Physics: Conference Series, 185(1), 012044. doi:10.1088/1742-6596/185/1/012044en_AU
dc.identifier.conferenceenddate28 November 2008en_AU
dc.identifier.conferencename8th Asian International Seminar on Atomic and Molecular Physicsen_AU
dc.identifier.conferenceplacePerth, Australiaen_AU
dc.identifier.conferencestartdate24 November 2008en_AU
dc.identifier.govdoc2832en_AU
dc.identifier.issn1742-6588en_AU
dc.identifier.issue1en_AU
dc.identifier.journaltitleJournal of Physics: Conference Seriesen_AU
dc.identifier.urihttp://dx.doi.org/10.1088/1742-6596/185/1/012044en_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/2685en_AU
dc.identifier.volume185en_AU
dc.language.isoenen_AU
dc.publisherInstitute of Physicsen_AU
dc.subjectPositron computed tomographyen_AU
dc.subjectClinical trialsen_AU
dc.subjectRadiopharmaceuticalsen_AU
dc.subjectMagnetic resonanceen_AU
dc.subjectNanostructuresen_AU
dc.subjectProbesen_AU
dc.titlePositrons as imaging agents and probes in nanotechnology.en_AU
dc.typeConference Paperen_AU
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Suzanne_V_Smith_2009_J._Phys. _Conf._Ser._185_012044 (2).pdf
Size:
699.14 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Conference Publications