Segmentation of small animal PET/CT mouse brain scans using an MRI-based 3D digital atlas: application in a neuroinflammation mouse model.

Simple item page
dc.contributor.authorDelzescaux, Ten_AU
dc.contributor.authorLebenberg, Jen_AU
dc.contributor.authorRaguet, Hen_AU
dc.contributor.authorHantraye, Pen_AU
dc.contributor.authorSouedet, Nen_AU
dc.contributor.authorGrégoire, MCen_AU
dc.date.accessioned2011-01-28T03:27:07Zen_AU
dc.date.available2011-01-28T03:27:07Zen_AU
dc.date.issued2010-09-02en_AU
dc.date.statistics2010-09-02en_AU
dc.description.abstractThe work reported in this paper aimed at developing and testing an automated method to calculate the biodistribution of a specific PET tracer in mouse brain PET/CT images using an MRI-based 3D digital atlas. Surface-based registration strategy and affine transformation estimation were considered. Such an approach allowed overcoming the lack of anatomical information in the inner regions of PET/CT brain scans. Promising results were obtained in one mouse (on two scans) and will be extended to a neuroinflammation mouse model to characterize the pathology and its evolution. Major improvements are expected regarding automation, time computation, robustness and reproducibility of mouse brain segmentation. Due to its generic implementation, this method could be successfully applied to PET/CT brain scans of other species (rat, primate) for which 3D digital atlases are available. © 2011 IEEEen_AU
dc.identifier.booktitleProceedings of the 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Societyen_AU
dc.identifier.citationDelzescaux, T., Lebenberg, J., Raguet, T., Hantraye, P., Souedet, N. & Grégoire, M. C. (2010). Segmentation of small animal PET/CT mouse brain scans using an MRI-based 3D digital atlas: application in a neuroinflammation mouse model. Paper presented to the 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'10) - "Merging Medical Humanism and Technology", 31st August - 4th September 2010. In Proceedings of the 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (pp. 3097-3100, ThDPo06.5). Buenos Aires, Argentina: Buenos Aires Sheraton Hotel. doi:10.1109/IEMBS.2010.5626106en_AU
dc.identifier.conferenceenddate4 September 2010en_AU
dc.identifier.conferencename32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'10) - 'Merging Medical Humanism and Technology'en_AU
dc.identifier.conferenceplaceBuenos Aires, Argentinaen_AU
dc.identifier.conferencestartdate31 August 2010en_AU
dc.identifier.govdoc3171en_AU
dc.identifier.isbn9781424441235en_AU
dc.identifier.issn1557-170Xen_AU
dc.identifier.pagination3097-3100en_AU
dc.identifier.urihttp://dx.doi.org/10.1109/IEMBS.2010.5626106en_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/2959en_AU
dc.language.isoenen_AU
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en_AU
dc.subjectRodentsen_AU
dc.subjectBrainen_AU
dc.subjectInflammationen_AU
dc.subjectMagnetic resonanceen_AU
dc.subjectImagesen_AU
dc.subjectPositron computed tomographyen_AU
dc.titleSegmentation of small animal PET/CT mouse brain scans using an MRI-based 3D digital atlas: application in a neuroinflammation mouse model.en_AU
dc.typeConference Presentationen_AU
Files
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Conference Publications