Radiochemical separation and quality assessment for the 68Zn target based 64Cu radioisotope production

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dc.contributor.authorLe, VSen_AU
dc.contributor.authorPellegrini, PAen_AU
dc.contributor.authorKatsifis, Aen_AU
dc.contributor.authorHowse, Jen_AU
dc.contributor.authorGreguric, Ien_AU
dc.date.accessioned2011-06-02T03:07:14Zen_AU
dc.date.available2011-06-02T03:07:14Zen_AU
dc.date.issued2008-08-01en_AU
dc.date.statistics2011-06-01en_AU
dc.description.abstractThe radiochemical separation of the different radionuclides (64Cu, 67Cu, 67Ga, 66Ga, 56Ni, 57Ni, 55Co, 56Co, 57Co, 65Zn, 196Au ) induced in the Ni supported Cu substrate – 68Zn target system, which was bombarded with the 29.0 MeV proton beam, was performed by ion-exchange chromatography using successive isocratic and/or concentration gradient elution techniques. The overlapped gamma-ray spectrum analysis method was developed to assess the 67Ga and 67Cu content in the 64Cu product and even in the post-67Ga production 68Zn target solution without the support of radiochemical separation. This method was used for the assessment of 64+67Cu radioisotope separation from 67Ga , the quality control of 64Cu product and the determination of the 68Zn (p,2p)67Cu reaction yield. The improvement in the targetry and the optimization of proton beam energy for the 68Zn target based 64Cu and 67Ga production were proposed based on the stopping power and range of the incident proton and on the excitation functions, reaction yields and different radionuclides induced in the target system. © 2008, Springer.en_AU
dc.identifier.citationLe, V.S., Pellegrini, P., Katsifis A., Howse J., & Greguric I., (2008). Radiochemical separation and quality assessment for the 68Zn target based 64Cu radioisotope production. Journal of Radioanalytical and Nuclear Chemistry, 277(2), 451–466. doi:10.1007/s10967-007-7143-xen_AU
dc.identifier.govdoc3384en_AU
dc.identifier.issn0236-5731en_AU
dc.identifier.issue2en_AU
dc.identifier.journaltitleJournal of Radioanalytical and Nuclear Chemistryen_AU
dc.identifier.pagination451-466en_AU
dc.identifier.urihttp://dx.doi.org/10.1007/s10967-007-7143-xen_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/3591en_AU
dc.identifier.volume277en_AU
dc.language.isoenen_AU
dc.publisherSpringeren_AU
dc.subjectZinc 68en_AU
dc.subjectCopper 64en_AU
dc.subjectRadioisotopesen_AU
dc.subjectCyclotronsen_AU
dc.subjectIon exchange chromatographyen_AU
dc.subjectProton beamsen_AU
dc.titleRadiochemical separation and quality assessment for the 68Zn target based 64Cu radioisotope productionen_AU
dc.typeJournal Articleen_AU
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