Measurement of glucose exclusion from the fully hydrated DOPE inverse hexagonal phase

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dc.contributor.authorKent, Ben_AU
dc.contributor.authorGarvey, CJen_AU
dc.contributor.authorLenné, Ten_AU
dc.contributor.authorPorcar, Len_AU
dc.contributor.authorGaramus, VMen_AU
dc.contributor.authorBryant, Gen_AU
dc.date.accessioned2010-06-15T04:27:28Zen_AU
dc.date.available2010-06-15T04:27:28Zen_AU
dc.date.issued2010-03-21en_AU
dc.date.statistics2010-03-21en_AU
dc.description.abstractThe degree of exclusion of glucose from the inverse hexagonal HII phase of fully hydrated DOPE is determined using contrast variation small angle neutron scattering and small angle X-ray scattering. The presence of glucose is found to favour the formation of the non-lamellar HII phase over the fluid lamellar phase, over a wide range of temperatures, while having no significant effect on the structure of the HII phase. Glucose is preferentially excluded from the lipid–water interface resulting in a glucose concentration in the HII phase of less than half that in the coexisting aqueous phase. The degree of exclusion is quantified and the results are consistent with a hydration layer of pure water adjacent to the lipid head groups from which glucose is excluded. The osmotic gradient created by the difference in glucose concentration is determined and the influence of glucose on the phase behaviour of non-lamellar phase forming lipid systems is discussed. © 2010, Royal Society of Chemistryen_AU
dc.identifier.citationKent, B., Garvey, C. J., Lenné, T., Porcar, L., Garamus, V. M., & Bryant, G. (2010). Measurement of glucose exclusion from the fully hydrated DOPE inverse hexagonal phase. Soft Matter, 6(6), 1197-1202. doi:10.1039/b919086den_AU
dc.identifier.govdoc1744en_AU
dc.identifier.issn1744-683Xen_AU
dc.identifier.issue6en_AU
dc.identifier.journaltitleSoft Matteren_AU
dc.identifier.pagination1197-1202en_AU
dc.identifier.urihttp://dx.doi.org/10.1039/b919086den_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/1707en_AU
dc.identifier.volume6en_AU
dc.language.isoenen_AU
dc.publisherRoyal Society of Chemistryen_AU
dc.subjectGlucoseen_AU
dc.subjectSmall angle scatteringen_AU
dc.subjectPhase studiesen_AU
dc.subjectLipidsen_AU
dc.subjectCrystal structureen_AU
dc.subjectHexagonal latticesen_AU
dc.titleMeasurement of glucose exclusion from the fully hydrated DOPE inverse hexagonal phaseen_AU
dc.typeJournal Articleen_AU
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