High pressure liquid chromatographic assay of technetium in solutions of sodium pertechnetate produced at the AAEC Research Establishment.

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dc.contributor.authorFarrington, KJen_AU
dc.date.accessioned2007-11-22T04:06:32Zen_AU
dc.date.accessioned2010-04-30T04:43:01Zen_AU
dc.date.available2007-11-22T04:06:32Zen_AU
dc.date.available2010-04-30T04:43:01Zen_AU
dc.date.issued1985-12en_AU
dc.description.abstractHigh pressure liquid chromatography (HPLC) is used for the assay of nanogram quantities of technetium and to determine technetium in decayed pharmaceutical products derived from three methods of manufacture. These methods of manufacture give comparably low levels of technetium-99 at the time of collection of the solution. However when the solutions are used to produce ready-to-inject technetium-99m high levels of technetium-99 are present at the time of calibration which is the day after the collection date. Where sensitive reagent kits are to be labelled freshly collected solutions of technetium-99m should be used. The HPLC assay is a valuable technique for the quality control of technetium-based radiopharmaceuticals and for investigation of methods of manufacture of technetium-99m. Experimental studies confirmed the findings of previous workers.en_AU
dc.identifier.citationFarrington, K. J. (1985). High pressure liquid chromatographic assay of technetium in solutions of sodium pertechnetate produced at the AAEC Research Establishment. (AAEC/E619). Lucas Heights NSW: Australian Atomic Energy Commission.en_AU
dc.identifier.govdoc962en_AU
dc.identifier.isbn0642598185en_AU
dc.identifier.otherAAEC-E-619en_AU
dc.identifier.placeofpublicationLucas Heights, New South Walesen_AU
dc.identifier.urihttp://apo.ansto.gov.au/dspace/handle/10238/31en_AU
dc.language.isoen_auen_AU
dc.publisherAustralian Atomic Energy Commissionen_AU
dc.subjectRadiopharmaceuticalsen_AU
dc.subjectTechnetium 99en_AU
dc.subjectLiquid column chromatographyen_AU
dc.subjectSodium compoundsen_AU
dc.subjectIsotope productionen_AU
dc.titleHigh pressure liquid chromatographic assay of technetium in solutions of sodium pertechnetate produced at the AAEC Research Establishment.en_AU
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