Development of an exchange-labelling procedure and investigation of the radiochemical stability and biodistribution characteristics for (131I) meta-iodobenzylguanidine sulphate (131I) MIBG
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Date
1989-08
Journal Title
Journal ISSN
Volume Title
Publisher
Australian Nuclear Science and Technology Organisation
Abstract
A simple exchange-labelling procedure for the radioiodination of meta-lobobenzylguanidine (MIBG) has been developed which facilitates the production of (131I) MIBG both quickly and efficiently. Stability studies indicate that labelled material if stored at reduced temperature undergoes little breakdown. Comparative biodistribution studies with a commercial source has been used to authenticate both the identity and purity of the product.
Description
Keywords
Radioisotopes, Radioactive materials, Sulfates, Distribution
Citation
Jenkinson, A. V., Maddalena, D. J., Snowdon, G. M., & Sorby, P. J. (1989). Development of an exchange-labelling procedure and investigation of the radiochemical stability and biodistribution characteristics for (131I) meta-iodobenzylguanidine sulphate (131I) MIBG. (ANSTO/E696). Lucas Heights, NSW: Australian Nuclear Science and Technology Organisation.