Pharmacological evaluation of a novel 18F-benzamide with high uptake and specificity to melanotic tissues as a PET diagnostic agent for melanoma

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dc.contributor.authorBerghofer, PJen_AU
dc.contributor.authorTaylor, SRen_AU
dc.contributor.authorBallantyne, Pen_AU
dc.contributor.authorPham, TQen_AU
dc.contributor.authorLoc’h, Cen_AU
dc.contributor.authorWyatt, NAen_AU
dc.contributor.authorNguyen, VHen_AU
dc.contributor.authorDenoyer, Den_AU
dc.contributor.authorHicks, RJen_AU
dc.contributor.authorGrégoire, MCen_AU
dc.contributor.authorKatsifis, Aen_AU
dc.contributor.authorGreguric, IDen_AU
dc.date.accessioned2025-07-31T13:13:12Zen_AU
dc.date.available2025-07-31T13:13:12Zen_AU
dc.date.issued2013-05en_AU
dc.date.statistics2025-05-15en_AU
dc.description.abstractWith distinct increases in incidence and mortality of melanoma worldwide our objective was to prepare radiolabel and evaluate [18F]MEL054; an enticing novel melanin targeting PET radiopharmaceutical whose characteristics have been taken from our previously reported iodinated molecules [123I]MEL037 and [123I]MEL008. As the chemistry of [18F]MEL054 can be simply translated to an iodine based [131I]radiopharmaceutical this is our first phase in creating an effective diagnostic/therapeutic pair targeting metastatic melanoma. © Wileyen_AU
dc.identifier.articlenumberS9en_AU
dc.identifier.citationBerghofer, P., Taylor, S. R., Ballantyne, P., Pham, T. Q., Loc’h, C., Wyatt, N., Nguyen, V. H., Denoyer, D., Hicks, R. J., Gregoire, M., Katsifis, A., & Greguric, I. (2013). Pharmacological evaluation of a novel 18F-benzamide with high uptake and specificity to melanotic tissues as a PET diagnostic agent for melanoma. Presentation to the 20th International Symposium on Radiopharmaceutical Sciences, 12-17 May 2013, Jeju, South Korea. In Journal of Labelled Compounds and Radiopharmaceuticals, 56(S1), S9. doi:10.1002/jlcr.3057en_AU
dc.identifier.conferenceenddate2013-05-17en_AU
dc.identifier.conferencename20th International Symposium on Radiopharmaceutical Sciencesen_AU
dc.identifier.conferenceplaceJeju, South Koreaen_AU
dc.identifier.conferencestartdate2013-05-12en_AU
dc.identifier.issueS1en_AU
dc.identifier.journaltitleJournal of Labelled Compounds and Radiopharmaceuticalsen_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/16384en_AU
dc.identifier.volume56en_AU
dc.language.isoenen_AU
dc.publisherWileyen_AU
dc.relation.urihttps://doi.org/10.1002/jlcr.3057en_AU
dc.subjectPharmacologyen_AU
dc.subjectFluorine 18en_AU
dc.subjectNeoplasmsen_AU
dc.subjectPositron computed tomographyen_AU
dc.subjectLabellingen_AU
dc.subjectDiagnostic techniquesen_AU
dc.subjectRadiopharmaceuticalsen_AU
dc.subjectChemistryen_AU
dc.subjectIodineen_AU
dc.subjectTumor cellsen_AU
dc.titlePharmacological evaluation of a novel 18F-benzamide with high uptake and specificity to melanotic tissues as a PET diagnostic agent for melanomaen_AU
dc.typeConference Presentationen_AU
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