Beryllium in contaminated soils: implication of beryllium bioaccessibility by different exposure pathways

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dc.contributor.authorIslam, MRen_AU
dc.contributor.authorSanderson, Pen_AU
dc.contributor.authorNaidu, Ren_AU
dc.contributor.authorPayne, TEen_AU
dc.contributor.authorJohansen, MPen_AU
dc.contributor.authorBari, ASMFen_AU
dc.contributor.authorRahman, MMen_AU
dc.date.accessioned2024-08-22T03:43:25Zen_AU
dc.date.available2024-08-22T03:43:25Zen_AU
dc.date.issued2022-01-05en_AU
dc.date.statistics2024-05-02en_AU
dc.description.abstractInhalation exposure and beryllium (Be) toxicity are well-known, but research on bioaccessibility from soils via different exposure pathways is limited. This study examined soils from a legacy radioactive waste disposal site using in vitro ingestion (Solubility Bioaccessibility Research Consortium [SBRC], physiologically based extraction test [PBET], in vitro gastrointestinal [IVG]), inhalation (simulated epithelial lung fluid [SELF]) and dynamic two-stage bioaccessibility (TBAc) methods, as well as 0.43 M HNO3 extraction. The results showed, 70 ± 4.8%, 56 ± 16.8% and 58 ± 5.7% of total Be were extracted (gastric phase [GP] + intestinal phase [IP]) in the SBRC, PBET, and IVG methods, respectively. Similar bioaccessibility of Be (~18%) in PBET-IP and SELF was due to chelating agents in the extractant. Moreover, TBAc–IP showed higher extraction (20.8 ± 2.0%) in comparison with the single-phase (SBRC–IP) result (4.8 ± 0.23%), suggesting increased Be bioaccessibility and toxicity in the gastrointestinal tract when the contamination derives from the inhalation route. The results suggested Be bioaccessibility depends on solution pH; time of extraction; soil reactive fractions (organic–inorganic); particle size, and the presence of chelating agents in the fluid. This study has significance for understanding Be bioaccessibility via different exposure routes and the application of risk-based management of Be-contaminated sites. © 2021 Elsevier B.V.en_AU
dc.description.sponsorshipThe authors would like to acknowledge ANSTO for providing assistance with sample collection and funding. They also acknowledge the University of Newcastle (UoN) and the Cooperative Research Centre for Contamination Assessment and Remediation of the Environment (CRC CARE), and the Electron Microscope and X-ray unit (central scientific service of UoN) for providing additional funding and technical and instrumental facilities.en_AU
dc.format.mediumPrint-Electronicen_AU
dc.identifier.articlenumber126757en_AU
dc.identifier.citationIslam, M. R., Sanderson, P., Naidu, R., Payne, T. E., Johansen, M. P., Bari, A. S. M. F., & Rahman, M. M. (2022). Beryllium in contaminated soils: implication of beryllium bioaccessibility by different exposure pathways. Journal of Hazardous Materials, 421, 126757. doi:10.1016/j.jhazmat.2021.126757en_AU
dc.identifier.issn0304-3894en_AU
dc.identifier.issn1873-3336en_AU
dc.identifier.journaltitleJournal of hazardous materialsen_AU
dc.identifier.urihttps://doi.org/10.1016/j.jhazmat.2021.126757en_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15662en_AU
dc.identifier.volume421en_AU
dc.languageEnglishen_AU
dc.language.isoenen_AU
dc.publisherElsevieren_AU
dc.subjectBerylliumen_AU
dc.subjectContaminationen_AU
dc.subjectRadioactive waste disposalen_AU
dc.subjectChelating agentsen_AU
dc.subjectSoilsen_AU
dc.subjectInhalationen_AU
dc.subjectHazardsen_AU
dc.subjectCarcinogensen_AU
dc.subjectDiseasesen_AU
dc.subjectHealth hazardsen_AU
dc.titleBeryllium in contaminated soils: implication of beryllium bioaccessibility by different exposure pathwaysen_AU
dc.typeJournal Articleen_AU
dcterms.dateAccepted2021-07-25en_AU
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