A general synthesis of benzoazepinoindoles – a new class of heterocycles
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Date
2019-10-09
Journal Title
Journal ISSN
Volume Title
Publisher
Thieme
Abstract
A new class of heterocyclic compounds, namely the benzoazepinoindolones, has been synthesised through a base-catalysed cyclisation reaction of 1,4-bis(2-aminophenyl)-2-phenylbutane-1,4-dione derivatives and features the prominent seven-membered azepine ring moiety. This synthesis has considerable scope for the rapid generation of more complex structures and is inexpensive and generally applicable. © 2019 Georg Thieme Verlag
Description
Keywords
Indoles, Benzoates, Drugs, Synthesis, Dehydrocyclization, Heterocyclic compounds
Citation
Dobrowolski, J. C., Nguyen, D. H., Fraser, B. H., Bhadbhade, M., Black, D. S., & Kumar, N. (2019). A general synthesis of benzoazepinoindoles–a new class of heterocycles. Synlett, 30(18), 2081-2085. doi:10.1055/s-0039-1690700