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Gadolinium as an element for neutron capture therapy

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Plenum Press

Abstract

Gadolinium is being studied as an alternate active element to B for Neutron Capture Therapy (NCT). The advantages of Gd-157 as compared to B-10 are that Gd-157 has a very large thermal neutron cross section (455,000 b), and Gd containing compounds that target tumors are being developed as MRI contrast agents. A disadvantage is that the products of the Gd + n reaction, gamma rays and Auger electrons, do not appear to be as well suited to NCT as the products of the B + n reaction, but these still may be effective in destroying tumors. Because of the advantages of Gd, an investigation of Gd as an element for NCT is proceeding at Brookhaven National Laboratory (BNL)1. © Plenum Press

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Physical copy held by ANSTO Library at DDC. 616.9940642/3

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Brugger, R. M., Liu, H. B., Laster, B. H., Gordon, C. R., Greenberg, D. D., & Warkentien, L. S. (1992). Gadolinium as an element for neutron capture therapy. Paper presented to the Fifth International Symposium on Neutron Capture Therapy for Cancer, September 13-17, Columbus, Ohio, USA. In Soloway, A. H., Barth, R. F., Carpenter, D. E. (eds) Advances in Neutron Capture Therapy, (pp. 225-229). Boston, MA : Plenum Press.

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