Synchrotron IR-microspectroscopy-based visualization of molecular and chemical interactions between dental cement, biomimetic composite and native dental tissue

Simple item page
dc.contributor.authorGoloshchapov, DLen_AU
dc.contributor.authorKashkarov, VMen_AU
dc.contributor.authorIppolitov, YAen_AU
dc.contributor.authorIppolitov, IYen_AU
dc.contributor.authorVongsvivut, JPen_AU
dc.contributor.authorSeredin, PVen_AU
dc.date.accessioned2024-01-12T00:16:35Zen_AU
dc.date.available2024-01-12T00:16:35Zen_AU
dc.date.issued2019-08-01en_AU
dc.date.statistics2023-12-11en_AU
dc.descriptionThe abstract is also available in Russian.en_AU
dc.description.abstractThe low affinity of composite materials for the hard tissue of human teeth poses a challenge to restorative dentists. This study was undertaken to explore molecular and chemical characteristics of the interface between the dental cement, the buffer layer formed from a next generation biomimetic material that mimics the organic mineral composition of human enamel and dentin, and the intact native hard dental tissue. Seven plane-parallel dental slices were analyzed using synchrotron IR microspectroscopy. The obtained absorption spectra of functional molecular groups were organized into cluster maps. This allowed us to identify the intact tissue, the adhesive agent and the biomimetic layer at their interface and to localize and measure concentrations of functional groups involved in the integration of the biomimetic composite into the hard tissue of the human tooth. The proposed biomimetic material is based on nanocrystal carbonate-substituted calcium hydroxyapatite synthesized from a biogenic calcium source and a complex of basic polar amino acids copying the composition of the human tooth and can form a functional bond with hard dental tissue. © 2019 The Authors. Open access under Creative Commons Attribution 4.0 International (CC BY 4.0) License.en_AU
dc.description.sponsorshipThe study was supported by the Russian Science Foundation (Grant 16-15-00003). IR microspectroscopy was conducted at the Australian Synchrotron.en_AU
dc.identifier.citationGoloshchapov, D. L., Kashkarov, V. M., Ippolitov, Y. A., Ippolitov, I. Y., Vongsvivut, J., & Seredin, P. V. (2019). Synchrotron IR-microspectroscopy-based visualization of molecular and chemical interactions between dental cement, biomimetic composite and native dental tissue. Bulletin of RSMU, (4), 71-78. doi:10.24075/brsmu.2019.047en_AU
dc.identifier.issn2542–1204en_AU
dc.identifier.journaltitleBulletin of RSMUen_AU
dc.identifier.pagination71-78en_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15336en_AU
dc.identifier.volume4en_AU
dc.language.isoenen_AU
dc.publisherPirogov Russian National Research Medical Universityen_AU
dc.relation.urihttps://doi.org/10.24075/brsmu.2019.047en_AU
dc.subjectBiomimeticsen_AU
dc.subjectTeethen_AU
dc.subjectDentistryen_AU
dc.subjectSpectroscopyen_AU
dc.subjectSynchrotron radiationen_AU
dc.subjectDentinen_AU
dc.subjectNanocrystalsen_AU
dc.titleSynchrotron IR-microspectroscopy-based visualization of molecular and chemical interactions between dental cement, biomimetic composite and native dental tissueen_AU
dc.typeJournal Articleen_AU
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
synchrotron-ir-microspectroscopy-based-visualization-of-molecular-and-chemical-interactions-between-dental-cement-biomimetic-composite-and-native-dental-tissue.pdf
Size:
7.51 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.63 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal Articles