Positron emission tomography coincidence detection with photon polarization correlation

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dc.contributor.authorMcNamara, ALen_AU
dc.contributor.authorWu, KWen_AU
dc.contributor.authorBoardman, DAen_AU
dc.contributor.authorReinhard, MIen_AU
dc.contributor.authorKuncic, Zen_AU
dc.date.accessioned2023-06-23T05:18:52Zen_AU
dc.date.available2023-06-23T05:18:52Zen_AU
dc.date.issued2013-02-09en_AU
dc.date.statistics2023-04-20en_AU
dc.description.abstractTwo-photon annihilation quanta are emitted in a pure quantum state and when detected in coincidence, the photon pairs possess orthogonal polarizations. We propose that this polarization correlation can be exploited in Positron Emission Tomography (PET), which relies crucially on accurate coincidence detection of photon pairs. In this proof of concept study, we investigate how photon polarization information can be exploited in PET imaging by developing a method to discern true coincidences using the polarization correlation of annihilation pairs. We demonstrate that the unique identification of true photon pairs with their polarization correlation can dramatically enhance overall PET image quality, especially for high emission rates, when conventional, energy- based coincidence detection methods become increasingly unreliable. Our results suggest that polarization-based coincidence detection offers new prospects for in vivo molecular imaging with next-generation PET systems. © 2013 Society of Photo-Optical Instrumentation Engineers (SPIE).en_AU
dc.identifier.articlenumber86681Uen_AU
dc.identifier.booktitleProceedings SPIE 8668, Medical Imaging 2013: Physics of Medical Imagingen_AU
dc.identifier.citationMcNamara, A. L., Wu, K., Boardman, D., Reinhard, M. I. & Kuncic, Z. (2013). Positron emission tomography coincidence detection with photon polarization correlation. Paper presented to SPIE Medical Imaging 2013, Orlando, Florida, USA, 9 - 14 February 2013. In Proceedings SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 86681U. doi:10.1117/12.2007794en_AU
dc.identifier.conferenceenddate14 February 2013en_AU
dc.identifier.conferencenameSPIE Medical Imaging 2013en_AU
dc.identifier.conferenceplaceFlorida, USAen_AU
dc.identifier.conferencestartdate9 February 2013en_AU
dc.identifier.issue6en_AU
dc.identifier.urihttps://doi.org/10.1117/12.2007794en_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15067en_AU
dc.identifier.volumeSPIE 8668en_AU
dc.language.isoenen_AU
dc.publisherSPIEen_AU
dc.subjectPositron computed tomographyen_AU
dc.subjectPhotonsen_AU
dc.subjectPolarizationen_AU
dc.subjectQuantum statesen_AU
dc.subjectParticle interactionsen_AU
dc.subjectAnnihilationen_AU
dc.titlePositron emission tomography coincidence detection with photon polarization correlationen_AU
dc.typeConference Paperen_AU
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