Characterization of prompt gamma rays for in-vivo range verification in hadron therapy: a geant4 simulation study

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dc.contributor.authorZarifi, Men_AU
dc.contributor.authorGuatelli, Sen_AU
dc.contributor.authorQi, Yen_AU
dc.contributor.authorBolst, Den_AU
dc.contributor.authorProkopovich, DAen_AU
dc.contributor.authorRosenfeld, ABen_AU
dc.date.accessioned2023-11-23T22:22:55Zen_AU
dc.date.available2023-11-23T22:22:55Zen_AU
dc.date.issued2018-02-06en_AU
dc.date.statistics2023-07-04en_AU
dc.description.abstractPrompt gamma (PG) rays have been proposed for in-vivo beam range verification during treatment delivery. As a secondary by-product emitted almost instantaneously upon ion-nuclear interaction, PG rays offer real-time tracking of the Bragg peak (BP). However their detection is challenging since they have a broad energy spectrum with interference from neutrons and stray gamma rays. Numerous approaches have been proposed to utilise PG for in-vivo beam range verification. In this work, Geant4 Monte Carlo (MC) simulations have been used to study the spectral, spatial, temporal and angular distribution characteristics of PG emission and detection from hadron radiation fields of varying energy. Proton, 12C and 4He beams irradiated homogeneous water phantoms. These studies will provide valuable information for the development of clinically suitable and reliable PG detector systems. © The Authors. Open Access.en_AU
dc.identifier.articlenumber012030en_AU
dc.identifier.citationZarifi, M., Guatelli, S., Qi, Y., Bolst, D., Prokopovich, D., & Rosenfeld, A. (2019). Characterization of prompt gamma rays for in-vivo range verification in hadron therapy: a Geant4 simulation study. Paper presented to MMD & ITRO 2018, Mini-Micro-Nano-Dosimetry and Innovative Technologies in Radiation Oncology Workshop, Mantra Mooloolaba-Beach, Queensland, Australia, February 6th-11th 2018. In Journal of Physics: Conference Series, 1154(1), 012030. doi:10.1088/1742-6596/1154/1/012030en_AU
dc.identifier.conferenceenddate2018-02-11en_AU
dc.identifier.conferencenameMMD & ITRO 2018, Mini-Micro-Nano-Dosimetry and Innovative Technologies in Radiation Oncology Workshopen_AU
dc.identifier.conferenceplaceMooloolaba, Queenslanden_AU
dc.identifier.conferencestartdate2018-02-06en_AU
dc.identifier.issue1en_AU
dc.identifier.journaltitleJournal of Physics: Conference Seriesen_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15238en_AU
dc.identifier.volume1154en_AU
dc.language.isoenen_AU
dc.publisherInstitute of Physics Publishingen_AU
dc.relation.urihttps://iopscience.iop.org/article/10.1088/1742-6596/1154/1/012030/pdfen_AU
dc.subjectIn vivoen_AU
dc.subjectBragg curveen_AU
dc.subjectEnergyen_AU
dc.subjectNeutronsen_AU
dc.subjectPhantomsen_AU
dc.subjectReal time systemsen_AU
dc.subjectAngular distributionen_AU
dc.titleCharacterization of prompt gamma rays for in-vivo range verification in hadron therapy: a geant4 simulation studyen_AU
dc.typeConference Paperen_AU
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