Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation

dc.contributor.authorTaba, STen_AU
dc.contributor.authorLewis, Sen_AU
dc.contributor.authorBaran, PMen_AU
dc.contributor.authorArhatari, BDen_AU
dc.contributor.authorNesterets, YIen_AU
dc.contributor.authorMayo, SCen_AU
dc.contributor.authorThompson, Den_AU
dc.contributor.authorFox, Jen_AU
dc.contributor.authorKumar, Ben_AU
dc.contributor.authorProdanovic, Zen_AU
dc.contributor.authorHäusermann, Den_AU
dc.contributor.authorMasimenko, Aen_AU
dc.contributor.authorHall, CJen_AU
dc.contributor.authorDimmock, Men_AU
dc.contributor.authorPavlov, KMen_AU
dc.contributor.authorPeele, AGen_AU
dc.contributor.authorQuiney, HMen_AU
dc.contributor.authorLockie, Den_AU
dc.contributor.authorTromba, Gen_AU
dc.contributor.authorGureyev, TEen_AU
dc.contributor.authorBrennan, PCen_AU
dc.date.accessioned2024-02-29T01:16:51Zen_AU
dc.date.available2024-02-29T01:16:51Zen_AU
dc.date.issued2020-05-22en_AU
dc.date.statistics2023-04-27en_AU
dc.description.abstractPropagation-based phase-contrast CT (PB-CT) is a novel imaging technique that visualises variations in both X-ray attenuation and refraction. This study aimed to compare the clinical image quality of breast PB-CT using synchrotron radiation with conventional absorption-based CT (AB-CT), at the same radiation dose. Seven breast mastectomy specimens were scanned and evaluated by a group of 14 radiologists and medical imaging experts who assessed the images based on seven radiological image quality criteria. Visual grading characteristics (VGC) were used to analyse the results and the area under the VGC curve was obtained to measure the differences between the two techniques. For six image quality criteria (overall quality, perceptible contrast, lesion sharpness, normal tissue interfaces, calcification visibility and image noise), PB-CT images were superior to AB-CT images of the same dose (AUCVGC: 0.704 to 0.914, P≤.05). For the seventh criteria (artefacts), PB-CT images were also rated better than AB-CT images (AUCVGC: 0.647) but the difference was not significant. The results of this study provide a solid basis for future experimental and clinical protocols of breast PB-CT. © 2020 Society of Photo-Optical Instrumentation Engineers (SPIE).en_AU
dc.identifier.articlenumber115130Ten_AU
dc.identifier.booktitleProceedings Volume 11513, 15th International Workshop on Breast Imaging (IWBI2020)en_AU
dc.identifier.citationTaba, S. T., Lewis, S., Baran, P. M,, Arhatari, B., Nesterets, Y., Mayo, S., Thompson, D., Fox, J., Kumar, B., Prodanovic, Z., Hausermann, D., Maksimenko, A., Hall, C., Dimmock, M., Pavlov, K., Peele, A., Quiney, H., Lockie, D., Tromba, G., Gureyev, P., & Brennan, P. (2020). Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation. Paper presented to the 15th International Workshop on Breast Imaging, formerly the IWDM, 24 - 27 May 2020, Unversity Hall, Leuven, Belguim. In H. Bosmans, N. Marshall, C. Van Ongeval (eds), Proceedings Volume 11513, 15th International Workshop on Breast Imaging (IWBI2020), 115130T. doi:10.1117/12.2564053en_AU
dc.identifier.conferenceenddate2020-05-27en_AU
dc.identifier.conferencename15th International Workshop on Breast Imaging, formerly the IWDMen_AU
dc.identifier.conferenceplaceLeuven, Belguimen_AU
dc.identifier.conferencestartdate2020-05-24en_AU
dc.identifier.urihttps://doi.org/10.1117/12.2564053en_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15485en_AU
dc.identifier.volume11513en_AU
dc.language.isoenen_AU
dc.publisherSociety of Photo-Optical Instrumentation Engineers (SPIE)en_AU
dc.subjectMammary glandsen_AU
dc.subjectRadiation dosesen_AU
dc.subjectContrast mediaen_AU
dc.subjectImagesen_AU
dc.subjectAbsorptionen_AU
dc.subjectCAT scanningen_AU
dc.titleComparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiationen_AU
dc.typeConference Paperen_AU
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