Imaging breast microcalcifications using dark-field signal in propagation-based phase-contrast tomography

Simple item page
dc.contributor.authorAminzadeh, Aen_AU
dc.contributor.authorArhatari, BDen_AU
dc.contributor.authorMaksimenko, Aen_AU
dc.contributor.authorHall, CJen_AU
dc.contributor.authorHäusermann, Den_AU
dc.contributor.authorPeele, AGen_AU
dc.contributor.authorFox, Jen_AU
dc.contributor.authorKumar, Ben_AU
dc.contributor.authorProdanovic, Zen_AU
dc.contributor.authorDimmock, MRen_AU
dc.contributor.authorLockie, Den_AU
dc.contributor.authorPavlov, KMen_AU
dc.contributor.authorThompson, Den_AU
dc.contributor.authorMayo, SCen_AU
dc.contributor.authorPaganin, DMen_AU
dc.contributor.authorTavakoli, Aen_AU
dc.contributor.authorLewis, SJen_AU
dc.contributor.authorBrennan, PCen_AU
dc.contributor.authorQuiney, HMen_AU
dc.contributor.authorGureyev, TEen_AU
dc.date.accessioned2023-10-20T01:15:14Zen_AU
dc.date.available2023-10-20T01:15:14Zen_AU
dc.date.issued2021-11-24en_AU
dc.date.statistics2023-04-21en_AU
dc.description.abstractBreast microcalcifications are an important primary radiological indicator of breast cancer. However, microcalcification classification and diagnosis can be still challenging for radiologists due to limitations of the standard 2D mammography technique, including spatial and contrast resolution. In this study, we propose an approach to improve the detection of microcalcifications in propagation-based phase-contrast X-ray tomography (PB-CT) of breast tissues. Five fresh mastectomies containing microcalcifications were scanned at the Imaging and Medical beamline of the Australian Synchrotron at different X-ray energies and radiation doses. Both bright-field and dark-field images were extracted from the same data sets using different image processing methods [1]. A quantitative analysis was performed in terms of visibility and contrast-to-noise ratio of microcalcifications. The results show that the visibility of the microcalcifications in the dark-field images is more than two times higher compared to the bright-field images. Dark-field images have also provided more accurate information about the size and shape of the microcalcifications [2]. Therefore, dark-field PB-CT images are likely to help radiologists evaluate the probability of breast cancer more effectively. This work has been conducted in the course of developing a medical imaging facility at the Australian Synchrotron for advanced breast cancer imaging. © The Authorsen_AU
dc.identifier.citationAminzadeh, A., Arhatari, B., Maksimenko, A., Hall, C., Hausermann, D., Peele, A., Fox, J., Kumar, B., Prodanovic, Z., Dimmock, M., Lockie, D., Pavlov, K., Thompson, D., Mayo, S., Paganin, D., Tavakoil, A., Lewis, S., Brennan, P., Quiney, H., & Gureyev, T. (2021). Imaging breast microcalcifications using dark-field signal in propagation-based phase-contrast tomography. Presentation to the ANSTO User Meeting, 24-26 November 2021, Online. Retrieved from: https://events01.synchrotron.org.au/event/146/contributions/4278/en_AU
dc.identifier.conferenceenddate2011-11-26en_AU
dc.identifier.conferencenameANSTO User Meetingen_AU
dc.identifier.conferenceplaceOnlineen_AU
dc.identifier.conferencestartdate2021-11-24en_AU
dc.identifier.urihttps://events01.synchrotron.org.au/event/146/contributions/4278/en_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/15158en_AU
dc.language.isoenen_AU
dc.publisherAustralian Nuclear Science and Technology Organisationen_AU
dc.subjectMammary glandsen_AU
dc.subjectNeoplasmsen_AU
dc.subjectContrast mediaen_AU
dc.subjectBiomedical radiographyen_AU
dc.subjectTomographyen_AU
dc.subjectSignal-to-noise-ratioen_AU
dc.subjectImagesen_AU
dc.titleImaging breast microcalcifications using dark-field signal in propagation-based phase-contrast tomographyen_AU
dc.typeConference Abstracten_AU
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
OgrEWivv_926509.pdf
Size:
1.43 MB
Format:
Adobe Portable Document Format
Description:
Download
Thumbnail Image
Name:
contribution-110.pdf
Size:
363.79 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.63 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Conference Publications