Design considerations for the proposed HIFAR thermal and epithermal neutron capture therapy facilities

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dc.contributor.authorStorr, GJen_AU
dc.contributor.authorAllen, BJen_AU
dc.contributor.authorHarrington, BVen_AU
dc.contributor.authorDavis, LRen_AU
dc.contributor.authorElcombe, MMen_AU
dc.contributor.authorMeriaty, Hen_AU
dc.date.accessioned2026-01-02T06:24:17Zen_AU
dc.date.available2026-01-02T06:24:17Zen_AU
dc.date.issued1992en_AU
dc.date.statistics2025-11-24en_AU
dc.descriptionPhysical copies held by ANSTO Library at DDC: 616.994/7en_AU
dc.description.abstractAt the Australian Nuclear Science and Technology Organization (ANSTO) the 100kW reactor Moata has been used successfully for Boron Neutron Capture Therapy (BNCT) of murine melanoma xenografts. Envisaged large animal and human irradiations would require a beam from the High Flux Australian Reactor (HIFAR). Attaining a therapeutic beam for BCNT at HIFAR present a challenge in physical design and engineering, as there is restricted access to core neutrons. major modifications to the HIFAR shielding are precluded as this action would require a long shutdown and a significant and costly safety analysis. The only feasible existing beam tube that may provide a BNCT beam is the 28 cm diameter 10H re-entrant hole, located at the core mid-plane. The 10H end-plate is located approximately 9 cm from two outer core fuel elements, separated from them by D2O. The 10H facility is currently used for neutron diffraction studies, and has a collimator installed which reduces the beam to a 5 cm square hole. A description of the 10H beam hole is contained in a calculational optimization study of an epithermal beam for HIFAR. A major component of the study was a comparison of different filter combinations located at the core end of 10H to maximize therapeutic gain at depth in a one-dimensional phantom model. Dose rates in the phantom were shown to lie close to the lower limit of acceptability for BNCT. © Plenum Pressen_AU
dc.identifier.booktitleProgress in Neutron Capture Therapy for Canceren_AU
dc.identifier.citationStorr, G. J., Allen, B. J., Harrington, B. V., Elcombe, M. M., Meriaty, H., & Davis, L. R. (1992). Design considerations for the proposed HIFAR thermal and epithermal neutron capture therapy facilities. Paper presented to the Fourth International Symposium on Neutron Capture Therapy for Cancer, December 4-7, 1990, Sydney, Australia. In B. J. Allen, D. E. Moore, & B. V. Harrington, (Eds.). Progress in neutron capture therapy for cancer (pp. 79-82). New York, USA :Plenum Press.en_AU
dc.identifier.conferenceenddate1990-12-07en_AU
dc.identifier.conferencenameFourth International Symposium on Neutron Capture Therapy for Cancer,en_AU
dc.identifier.conferenceplaceSydney, Australiaen_AU
dc.identifier.conferencestartdate1990-12-04en_AU
dc.identifier.editorsB. J. Allen, D. E. Moore, & B. V. Harrington,en_AU
dc.identifier.isbn9781461364948en_AU
dc.identifier.pagination79-82en_AU
dc.identifier.placeofpublicationNew York, USAen_AU
dc.identifier.urihttps://doi.org/10.1007/978-1-4615-3384-9_15en_AU
dc.identifier.urihttps://apo.ansto.gov.au/handle/10238/16819en_AU
dc.languageEnglishen_AU
dc.language.isoenen_AU
dc.publisherPlenum Pressen_AU
dc.subjectDesignen_AU
dc.subjectEpithermal neutronsen_AU
dc.subjectFeasibility studiesen_AU
dc.subjectHIFAR Reactoren_AU
dc.subjectNeutron beamsen_AU
dc.subjectNeutron capture therapyen_AU
dc.subjectOptimizationen_AU
dc.subjectPhantomsen_AU
dc.subjectRadiation dosesen_AU
dc.titleDesign considerations for the proposed HIFAR thermal and epithermal neutron capture therapy facilitiesen_AU
dc.typeConference Paperen_AU
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