Using water quality and isotope studies to inform research in chronic kidney disease of unknown aetiology endemic areas in Sri Lanka

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dc.contributor.authorNikagolla, Cen_AU
dc.contributor.authorMeredith, KTen_AU
dc.contributor.authorDawes, L Aen_AU
dc.contributor.authorBanati, RBen_AU
dc.contributor.authorMillar, GJen_AU
dc.date.accessioned2023-02-09T23:34:23Zen_AU
dc.date.available2023-02-09T23:34:23Zen_AU
dc.date.issued2020-11-25en_AU
dc.date.statistics2022-11-16en_AU
dc.description.abstractChronic Kidney Disease of unknown aetiology (CKDu) is a major public health concern in dry climatic, agricultural regions of Sri Lanka. The chemistry of groundwater (the main source of drinking water) in the area has been studied extensively, in relation to the occurrence of CKDu. This paper investigates water quality studies published in CKDu affected areas of Sri Lanka and also presents a new data set of 27 hydrochemical and isotopic samples collected from groundwater wells in selected CKDu endemic areas in Sri Lanka. The study outcomes do not provide evidence of pollutants such as heavy metals in groundwater. However, the study identifies elevated concentrations of silica which requires further investigation. Two groups of groundwater have been identified based on the isotopic results suggesting different sources or origins. The available water quality data, including the data from this study, is not sufficient to answer questions on whether the chemistry of groundwater is related to the CKDu occurrence. However, this study identifies the importance of detailed investigation into degradation products of agrochemicals, the organic matter content and the influence of elevate silica concentration in groundwater. The study also provides research directions in the form of isotopic tracers and the frequency of sampling that is needed to capture potential pollutants in future groundwater quality studies in CKDu endemic areas in Sri Lanka. Crown Copyright © 2020 Published by Elsevier B.V.en_AU
dc.identifier.articlenumber140896en_AU
dc.identifier.citationNikagolla, C., Meredith, K. T., Dawes, L. A., Banati, R. B., & Millar, G. J. (2020). Using water quality and isotope studies to inform research in chronic kidney disease of unknown aetiology endemic areas in Sri Lanka. Science of the Total Environment, 745, 140896. doi:10.1016/j.scitotenv.2020.140896en_AU
dc.identifier.issn0048-9697en_AU
dc.identifier.journaltitleScience of the Total Environmenten_AU
dc.identifier.urihttps://doi.org/10.1016/j.scitotenv.2020.140896en_AU
dc.identifier.urihttps://apo.ansto.gov.au/dspace/handle/10238/14635en_AU
dc.identifier.volume745en_AU
dc.language.isoenen_AU
dc.publisherElsevieren_AU
dc.subjectWater qualityen_AU
dc.subjectIsotopesen_AU
dc.subjectKidneysen_AU
dc.subjectDiseasesen_AU
dc.subjectSri Lankaen_AU
dc.subjectAsiaen_AU
dc.subjectGround wateren_AU
dc.subjectPollutantsen_AU
dc.titleUsing water quality and isotope studies to inform research in chronic kidney disease of unknown aetiology endemic areas in Sri Lankaen_AU
dc.typeJournal Articleen_AU
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