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Title: Interaction of erythrocytes and hexavalent uranium compounds - an autoanalytical study.
Authors: Stuart, WI
Shying, ME
Keywords: Animal cells
Chemical analysis
Biological effects
In vitro
Issue Date: May-1980
Publisher: Australian Atomic Energy Commission
Citation: Stuart, W. I., & Shyling, M. E. (1980). Interaction of erythrocytes and hexavalent uranium compounds - an autoanalytical study. (AAEC/E480). Lucas Heights, NSW: Australian Atomic Energy Commission.
Abstract: An automated analytical system was devised to measure the kinetics of hemolysis by uranyl compounds. Accurate plots of percentage hemolysis v. time were obtained; these together with the corresponding differential curves show that hemolysis of plasma-free erythrocytes is a two-stage process. The first stage of hemolysis is particularly affected by pH and anion content of uranyl solutions and also by incubation of cell suspensions at 37 deg. before mixing with lysing solution. Complementary studies involving Coulter counting and microscopic observation established the general pattern of hemolysis and showed that cell agglutination is a prominent feature of the interaction of cells with uranyl solutions.
Gov't Doc #: 396
ISBN: 0642596883
Appears in Collections:Scientific and Technical Reports

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