Browsing by Author "Tallentire, SE"
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- ItemUnexpected low-temperature behaviour of piroxicam monohydrate(Wiley-VCH Verlag, 2013-03-18) Fucke, K; Edwards, AJ; Probert, MR; Tallentire, SE; Howard, JAK; Steed, JWUpon cooling the monohydrate of the anti-inflammatory drug piroxicam shows reversible splitting. The cell also shows an irregular contraction over temperature and has a memory effect of its thermal history. This is due to strongly hydrogen bonded chains present in the monohydrate, which allow the crystal domains to contract separately from each other. © 2013, Wiley-VCH Verlag.