Repository logo


ANSTO Publications Online

Welcome to the ANSTO Institutional Repository known as APO.

The APO database has been migrated to version 8.3. The functionality has changed, but the content remains the same.

ANSTO Publications Online is a digital repository for publications authored by ANSTO staff since 2007. The Repository also contains ANSTO Publications, such as Reports and Promotional Material. ANSTO publications prior to 2007 continue to be added progressively as they are in identified in the library. ANSTO authors can be identified under a single point of entry within the database. The citation is as it appears on the item, even with incorrect spelling, which is marked by (sic) or with additional notes in the description field.

If items are only held in hardcopy in the ANSTO Library collection notes are being added to the item to identify the Dewey Call number: as DDC followed by the number.

APO will be integrated with the Research Information System which is currently being implemented at ANSTO. The flow on effect will be permission to publish, which should allow pre-prints and post prints to be added where content is locked behind a paywall. To determine which version can be added to APO authors should check Sherpa Romeo. ANSTO research is increasingly being published in open access due mainly to the Council of Australian University Librarians read and publish agreements, and some direct publisher agreements with our organisation. In addition, open access items are also facilitated through collaboration and open access agreements with overseas authors such as Plan S.

ANSTO authors are encouraged to use a CC-BY licence when publishing open access. Statistics have been returned to the database and are now visible to users to show item usage and where this usage is coming from.

Discover

Communities in ANSTO Publications Online

Select a community to browse its collections.

Now showing 1 - 5 of 5

Recent Submissions

  • Thumbnail Image
    Item type: Item ,
    An analytic model for drag reduction in turbulent flow when polymers are present
    (University of Newcastle, 1983-11-28) Beattie, DRH
    A model is proposed for drag reduction by polymer additives. The model assumes (a) intermittency between polymer—coil agglomerates in the near—wall region; (b) extension of polymer coils in regions where turbulent energy production exceeds a threshold level; (c) a uniform layer of polymer coils on the wall side of the layer of extended polymers ; and (d) a shift of the origin of the logarithmic velocity profile equation from the wall to the wall side of this layer of uniform polymer coils. The model, and predictions based on it, are shown to be compatible with several observed drag reduction phenomena.
  • Thumbnail Image
    Item type: Item ,
    An extension of single phase flow turbulent pipe flow concepts to two-phase flow
    (UNSW Faculty Engineering, 1983) Beattie, DRH
    This thesis describes a series of investigations into the hydraulic and thermal characteristics of various turbulent two-phase pipe flows, arising from one particular way of extending to two-phase flow, concepts previously developed for single phase pipe flow, e.g. mixing length, turbulent core, wall boundary or sub-layer, roughness, Reynolds analogy, etc. This approach predicted a logarithmic core profile of local volumetric flux as a function of wall distance. Accounting for a range of different possible sub-layer fluid structures, it led to a dimensionless profile, and hence directly to a wall friction factor, in terms of dimensionless parameters chosen according to the type of sub-layer. A 'friction regime' concept was developed, with regimes classified by sub-layer type and two characteristic integers which serve to determine the profile. The relations developed were based on the analysis of world-wide experimental two-phase flow data, and a number of practically useful new friction factor correlations resulted. For a number of different 'friction regimes', the work was supplemented by additional models and analyses and applied to the prediction of average void fraction, heat transfer coefficient, critical heat flux, pulse propagation velocity and choked flow rate. In many cases, significant agreement was achieved between predictions and published data for which simultaneous measurements of several parameters guaranteed experimental consistency. Open Access - CC BY-NC-ND 3.0
  • Thumbnail Image
    Item type: Item ,
    Proceedings to the 58th Annual Conference of the Particle Therapy Cooperative Group (PTCOG58)
    (Elsevier, 2020-03) Particle Therapy Cooperative Group (PTCOG)
    No Abstract
  • Thumbnail Image
    Item type: Item ,
    Ionic liquid adsorption at the silica–oil interface revealed by neutron reflectometry
    (American Chemical Society, 2018-09-18) Cooper, PK; Li, H; Yepuri, NR; Nelson, A; Webber, GB; Le Brun, AP; Darwish, TA; Warr, GG; Atkin, R
    Previous nanotribology measurements demonstrated that 2 mol % of the oil-miscible ionic liquid (IL) trihexyltetradecyl­(phosphonium) bis­(2,4,4-trimethylpentyl)­phosphinate (P6,6,6,14 ( i C8)2PO2) diluted in octane lubricated as effectively as pure IL. However, until now the structure and composition of the lubricating adsorbed layer, which is critical for lubrication, was unknown. Here, the unconfined structure of the IL adsorbed layer at the oil–silica interface has been studied using neutron reflectometry. Multiple neutron contrasts revealed an 8 Å thick adsorbed layer, even at 60 and 80 °C. The ratio of cations and anions in the layer was investigated by synthesizing the IL with deuterated cations and measuring its reflectivity at the oil–silica interface. At 60 °C the layer was composed of 48 ± 6 mol % P6,6,6,14 + cations, 24 ± 2 mol % ( i C8)2PO2 – anions, and 28 ± 8 mol % octane, while at 80 °C the composition was 50 ± 2 mol % P6,6,6,14 +, 28 ± 2 mol % ( i C8)2PO2 – anions, and 22 ± 2 mol % octane. These results reinforce the importance of the judicious selection of IL cations and anions for charged surfaces and support their use in high-temperature applications. © 2018 American Chemical Society.
  • Thumbnail Image
    Item type: Item ,
    Daptomycin-loaded nanocarriers facilitate synergistic killing of methicillin-resistant staphylococcus aureus via lipid-mediated interactions and targeting
    (Oxford University Press (OUP), 2026-01-15) Jiang, JH; Lim, CX; Lai, XF; Kostoulias, XP; Morris, FC; Le Brun, AP; Wu, CM; Yepuri, NR; Shen, HH; Peleg, AY
    Preservation and augmentation of existing antimicrobials is crucial in combating antimicrobial resistance. Gram-positive bacteria, exemplified by Staphylococcus aureus, are among the most common human bacterial pathogens, with methicillin-resistant S. aureus (MRSA) now established globally. Daptomycin is a last-line anti-staphylococcal antimicrobial that uniquely targets the bacterial membrane with bactericidal effects. Here, we developed lipid-based nanoparticles, namely cubosomes, to encapsulate daptomycin for targeted delivery via lipid-mediated interactions. Daptomycin-loaded cubosomes synergistically killed 14 clinical MRSA isolates in vitro compared with daptomycin or cubosomes alone. This synergy between daptomycin and cubosome was mediated by cubosomes docking on the S. aureus cell surface, releasing daptomycin for membrane extraction and penetration, followed by lipid cubosome infusion into S. aureus membranes. Using a murine septicemia model, daptomycin-loaded cubosomes significantly reduced the organ bacterial burden of MRSA. Together, these data showed that multifunctional lipid nanocarriers can potentiate the bactericidal activity of daptomycin using a membrane-targeted trojan-horse-like mechanism. © The Author(s) 2025. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence.