In vivo evaluation of radiofluorinated caspase-3/7 inhibitors as radiotracers for apoptosis imaging and comparison with [18F]ML-10 in a stroke model in the rat
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Date
2016-02-01
Journal Title
Journal ISSN
Volume Title
Publisher
Springer Nature
Abstract
The first biological evaluation of two potent fluorine-18 radiolabelled inhibitors of caspase-3/7 was achieved in a cerebral stroke rat model to visualize apoptosis © 2016 Springer Nature
Description
Keywords
Fluorine 18, Ischemia, In vivo, Apoptosis, Cysteine, Enzyme inhibitors, Tracer techniques
Citation
Médoc, M., Dhilly, M., Matesic, L., Toutain, J., Krause-Heuer, A. M., Delamare, J., Fraser, B. H., Touzani, O., Barré, L., Greguric, I., & Sobrio, F. (2016). In vivo evaluation of radiofluorinated caspase-3/7 inhibitors as radiotracers for apoptosis imaging and comparison with [18F]ML-10 in a stroke model in the rat. Molecular Imaging and Biology, 18(1), 117-126. doi:10.1007/s11307-015-0865-1