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In vivo evaluation of radiofluorinated caspase-3/7 inhibitors as radiotracers for apoptosis imaging and comparison with [18F]ML-10 in a stroke model in the rat

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2016-02-01

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Springer Nature

Abstract

The first biological evaluation of two potent fluorine-18 radiolabelled inhibitors of caspase-3/7 was achieved in a cerebral stroke rat model to visualize apoptosis © 2016 Springer Nature

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Fluorine 18, Ischemia, In vivo, Apoptosis, Cysteine, Enzyme inhibitors, Tracer techniques

Citation

Médoc, M., Dhilly, M., Matesic, L., Toutain, J., Krause-Heuer, A. M., Delamare, J., Fraser, B. H., Touzani, O., Barré, L., Greguric, I., & Sobrio, F. (2016). In vivo evaluation of radiofluorinated caspase-3/7 inhibitors as radiotracers for apoptosis imaging and comparison with [18F]ML-10 in a stroke model in the rat. Molecular Imaging and Biology, 18(1), 117-126. doi:10.1007/s11307-015-0865-1

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https://doi.org/10.1007/s11307-015-0865-1
 http://apo.ansto.gov.au/dspace/handle/10238/9015

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