ANSTO Publications Online >
Journal Publications >
Journal Articles >

Please use this identifier to cite or link to this item:

Title: Nanofibrillar micelles and entrapped vesicles from biodegradable block copolymer/polyelectrolyte complexes in aqueous media
Authors: Salim, NV
Hameed, N
Hanley, TL
Waddington, LJ
Hartley, PG
Guo, Q
Issue Date: 9-Jul-2013
Publisher: ACS Publications
Citation: Salim, N. V., Hameed, N., Hanley, T. L., Waddington, L. J., Hartley, P. G., & Guo, Q. (2013). Nanofibrillar Micelles and Entrapped Vesicles from Biodegradable Block Copolymer/Polyelectrolyte Complexes in Aqueous Media. Langmuir, 29(29), 9240-9248.
Abstract: Here we report a viable route to fibrillar micelles and entrapped vesicles in aqueous solutions. Nanofibrillar micelles and entrapped vesicles were prepared from complexes of a biodegradable block copolymer poly(ethylene oxide)-block-poly(lactide) (PEO-b-PLA) and a polyelectrolyte poly(acrylic acid) (PAA) in aqueous media and directly visualized using cryogenic transmission electron microscopy (cryo-TEM). The self-assembly and the morphological changes in the complexes were induced by the addition of PAA/water solution into the PEO-b-PLA in tetrahydrofuran followed by dialysis against water. A variety of morphologies including spherical wormlike and fibrillar micelles, and both unilamellar and entrapped vesicles, were observed, depending on the composition, complementary binding sites of PAA and PEO, and the change in the interfacial energy. Increasing the water content in each [AA]/[EO] ratio led to a morphological transition from spheres to vesicles, displaying both the composition- and dilution-dependent micellar-to-vesicular morphological transitions. © 2013, American Chemical Society.
ISSN: 0743-7463
Appears in Collections:Journal Articles

Files in This Item:

There are no files associated with this item.

Items in APO are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback