ANSTO Publications Online >
Journal Publications >
Journal Articles >
Please use this identifier to cite or link to this item:
|Title: ||Olanzapine differentially affects 5-HT2A (and 2C) receptor mRNA expression in the rat brain|
|Authors: ||Huang, XF|
|Issue Date: ||10-Aug-2006|
|Publisher: ||ELSEVIER SCIENCE BV|
|Citation: ||Huang, X. F., Han, M., Huang, X., Zavitsanou, K., & Deng, C. (2006). Olanzapine differentially affects 5-HT2A (and 2C) receptor mRNA expression in the rat brain. Behavioural Brain Research, 171(2), 355-362.|
|Abstract: ||This study examined regional changes in rat brain mRNA levels encoding 5-HT2A and 5-HT2C receptors following chronic olanzapine treatment. The immediate effect (2 h after the last treatment) was a down-regulation of 5-HT2A receptor mRNA expression, predominantly in the hypothalamus, limbic system and striatum, while a rebound effect was observed 48 h later. 5-HT2C receptor mRNA expressions were decreased in the substantia nigra. Correlations between 5-HT2A receptor mRNA expression and total food intake, weight gain and energy efficiency were observed. © 2006, Elsevier Ltd.|
|Appears in Collections:||Journal Articles|
Files in This Item:
There are no files associated with this item.
Items in APO are protected by copyright, with all rights reserved, unless otherwise indicated.