A new approach to the estimation of radiopharmaceutical radiation dose distributions

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Date
1975-03
Journal Title
Journal ISSN
Volume Title
Publisher
Australian Atomic Energy Commission
Abstract
For a photon energy of 150 keV, the Monte Carlo technique of photon history simulation was used to obtain estimates of the dose distribution in a human phantom for three activity distributions relevant to diagnostic nuclear medicine. In this preliminary work, the number of photon histories considered was insufficient to produce complete dose contours and the dose distributions are presented in the form of colour-coded diagrams. The distributions obtained illustrate an important deficiency in the MIRD Schema for dose estimation. Although the Schema uses the same mathematical technique for calculating photon doses, the results are obtained as average values for the whole body and for complete organs. It is shown that the actual dose distributions, particularly those for the whole body, may differ significantly from the average value calculated using the MIRD Schema and published absorbed fractions.
Description
Keywords
Radiopharmaceuticals, Monte Carlo Method, Radiation dose distributions, Dosimetry, Mathematical models
Citation
Hetheringtom, E. L. R., & Wood, N. R. (1975). A new approach to the estimation of radiopharmaceutical radiation dose distributions. (AAEC/E350). Lucas Heights, NSW: Australian Atomic Energy Commission.