Haemolytic activity of uranium compounds: haemolysis by thermochemical derivatives of ammonium uranate.

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Date
1975-01
Journal Title
Journal ISSN
Volume Title
Publisher
Australian Atomic Energy Commission
Abstract
A study has been made of the haemolytic action on human erythrocytes by ammonium uranate (AU) and various thermochemical products of AU. These products were obtained by heating AU in hydrogen at 5ºC min-1 to various temperatures. Haemolysis has been interpreted in terms of a diffusion model which for each product yields a single parameter Kn, the haemolytic activity factor. The magnitude of Kn is a convenient measure of the ability of a powder to damage erythrocytes. The haemolytic activity of certain thermochemical derivatives indicates an exceptionally high potential for damage to erythrocytes. Infrared and thermoanalytical measurements have shown that the high activity of these products derives principally from a self-reduction reaction, induced by heating AU to 400-420ºC in hydrogen.
Description
Keywords
Uranium compounds, Diffusion, Ammonium compounds
Citation
Stuart, W. I., Tucker, A. D., Adams, R. B., & Smith H. E.(1975). Haemolytic activity of uranium compounds : haemolysis by thermochemical derivatives of ammonium uranate (AAEC/E311). Lucas Heights, NSW: Australian Atomic energy Commission, Research Establishment.