ANSTO Publications Online >
Journal Publications >
Journal Articles >

Please use this identifier to cite or link to this item:

Title: An investigation of inconsistent projections and artefacts in multi-pinhole SPECT with axially aligned pinholes.
Authors: Kench, P L
Lin, J
Grégoire, M-C
Meikle, S R
Keywords: PHANTOMS
Issue Date: 7-Dec-2011
Citation: Kench, P. L., Lin, J., Gregoire, M-C., & Meikle, S. R. (2011). An investigation of inconsistent projections and artefacts in multi-pinhole SPECT with axially aligned pinholes. Physics in Medicine and Biology, 56 (23), 7487-7503.
Abstract: Multiple pinholes are advantageous for maximizing the use of the available field of view (FOV) of compact small animal single photon emission computed tomography (SPECT) detectors. However, when the pinholes are aligned axially to optimize imaging of extended objects, such as rodents, multiplexing of the pinhole projections can give rise to inconsistent datawhich leads to ‘ghost point’ artefacts in the reconstructed volume. A novel four pinhole collimator with a baffle was designed and implemented to eliminate these inconsistent projections. Simulation and physical phantom studies were performed to investigate artefacts from axially aligned pinholes and the efficacy of the baffle in removing inconsistent data and, thus, reducing reconstruction artefacts. SPECT was performed using a Defrise phantom to investigate the impact of collimator design on FOV utilization and axial blurring effects. Multiple pinhole SPECT acquired with a baffle had fewer artefacts and improved quantitative accuracy when compared to SPECT acquired without a baffle. The use of four pinholes positioned in a square maximized the available FOV, increased acquisition sensitivity and reduced axial blurring effects. These findings support the use of a baffle to eliminate inconsistent projection data arising from axially aligned pinholes and improve small animal SPECT reconstructions. © 2011 IOP Publishing LTD
ISSN: 0031-9155
Appears in Collections:Journal Articles

Files in This Item:

There are no files associated with this item.

Items in APO are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback