|
Home |
| Browse | |
|
|
Communities & Collections |
|
|
Issue Date |
|
|
Author |
|
|
Title |
|
|
Subject |
| Sign on to: | |
|
|
Receive email updates |
|
|
My APO authorized users |
|
|
Edit Profile |
|
|
|
|
|
About DSpace |
ANSTO Publications Online >
Journal Publications >
Journal Articles >
Please use this identifier to cite or link to this item:
http://apo.ansto.gov.au/dspace/handle/10238/3759
|
| Title: | Tandem “Click” Reactions at Acetylene-Terminated Si(100) Monolayers |
| Authors: | Ciampi, S James, M Michaels, P Gooding, JJ |
| Keywords: | X-ray Spectroscopy Molecular Biology X-ray Photoelectron Spectroscopy DNA Oligonucleotides Silicon |
| Issue Date: | 7-Jun-2011 |
| Publisher: | American Chemical Society |
| Citation: | Ciampi, S., James, M., Michaels, P., Gooding, J.J. (2011). Tandem “Click” Reactions at Acetylene-Terminated Si(100) Monolayers, Langmuir, 27(11), 6940-6949. |
| Abstract: | We demonstrate a simple method for coupling alkynes to alkynes. The method involves tandem azide–alkyne cycloaddition reactions (“click†chemistry) for the immobilization of 1-alkyne species onto an alkyne modified surface in a one-pot procedure. In the case presented, these reactions take place on a nonoxidized Si(100) surface although the approach is general for linking alkynes to alkynes. The applicability of the method in the preparation of electrically well-behaved functionalized surfaces is demonstrated by coupling an alkyne-tagged ferrocene species onto alkyne-terminated Si(100) surfaces. The utility of the approach in biotechnology is shown by constructing a DNA sensing interface by derivatization of the acetylenyl surface with commercially available alkyne-tagged oligonucleotides. Cyclic voltametry, electrochemical impedance spectroscopy, X-ray photoelectron spectroscopy, and X-ray reflectometry are used to characterize the coupling reactions and performance of the final modified surfaces. These data show that this synthetic protocol gives chemically well-defined, electronically well-behaved, and robust (bio)functionalized monolayers on silicon semiconducting surfaces. © 2010, American Chemical Society |
| URI: | http://dx.doi.org/10.1021/la2013733 http://apo.ansto.gov.au/dspace/handle/10238/3759 |
| ISSN: | 0743-7463 |
| Appears in Collections: | Journal Articles |
Files in This Item: There are no files associated with this item. |
Items in APO are protected by copyright, with all rights reserved, unless otherwise indicated.
|
DSpace Software Copyright © 2002-2010 Duraspace - Feedback |