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Please use this identifier to cite or link to this item: http://apo.ansto.gov.au/dspace/handle/10238/3714

Title: Chemical synthesis and application of zirconium and titanium polymer compounds for the preparation of Tc-99m and Re-188 chromtographic generators
Authors: Le, VS
Keywords: Radioisotope Generators
Titanium Compounds
Molybdenum 99
Zirconium Compounds
Radioisotope Generators
NT1 Chemical Preparation
Issue Date: 3-Apr-2006
Publisher: IAEA’S coordinated research project 2nd research coornation meeting
Citation: Le V.S. (2006). Chemical synthesis and application of zirconium and titanium polymer compounds for the preparation of Tc-99m and Re-188 chromtographic generators. IAEA’S coordinated research project 2nd research coornation meeting. "Development of generator technologies for therapeutic radionuclides”, 3th-7th April. European Institute of Oncology, Milan, Italy.
Abstract: PZC adsorbent for the preparation of PZC based chromatographic Tc-99m and / or Re-188 generators was successfully synthesized and its chemical composition, molecular structure was determined. 99Mo and/or 188W -adsorption on PZC in different solutions and 99mTc and/or 188Re elution from PZC columns were investigated. Mo- adsorption capacity of about 285 mgMo/gPZC and Tc-99m elution yield of higher than 90% were achieved with PZC adsorbent. Mo-99 breakthrough of 0.015% and Molybdenum element breakthrough of lower than 5μg Mo/ml were found in Tc-99m eluate. W- adsorption capacity of about 520 mgW/gPZC and Re-188 elution yield of higher than 80% were also achieved with PZC adsorbent. W-188 breakthrough of 0.015% and Tungsten element breakthrough of lower than 5 μg W /ml were found in Tc-99m eluate. A good relationship between the W- or Mo-content of adsorption solution and the adsorption capacity, adsorption percentage, chemical breakthrough and relevant radionuclide elution yield was found.
URI: http://apo.ansto.gov.au/dspace/handle/10238/3714
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