A new N-terminal protecting group for peptide attachment to insoluble supports.
Loading...
Date
1978-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Australian Atomic Energy Commission
Abstract
Cobalt(III) active ester complexes [Co(en)2(NH2CHRCOOR')]-(CIOO3, where en is ethylenediamine, R is H or -CH2- and R1 is CH3, C2H5 or C3H7 , have been used to provide N-terminal protection before the attachment of peptides to insoluble polymeric supports. The protecting group can be removed readily and quantitatively using normal physiological parameters from peptides attached to non-crosslinked resins.
Description
Keywords
Peptides, Amino acids, Resins, Ethanol
Citation
Bentley, K. W. (1978). A new n-terminal protecting group for peptide attachment to insoluble supports (AAEC/E457). Lucas Heights, N.S.W.: Research Establishment, Australian Atomic Energy Commission.