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Title: In vivo PET imaging with [18F]FDG to explain improved glucose uptake in an apolipoprotein A-I treated mouse model of diabetes
Authors: Cochran, BJ
Ryder, WJ
Parmar, A
Tang, S
Reilhac, A
Arthur, A
Charil, A
Hamze, H
Barter, PJ
Kritharides, L
Meikle, SR
Grégoire, MC
Rye, K
Keywords: Diabetes mellitus
Positron computed tomography
Issue Date: 18-May-2016
Publisher: Springer Nature
Citation: Cochran, B. J., Ryder, W. J., Parmar, A., Tang, S., Reilhac, A., Arthur, A., Charil, A., Hamze, H., Barter, P. J., Kritharides, L. Meikle, S. R., Grégoire, M. C. & Rye, K. (2016). In vivo PET imaging with [18F] FDG to explain improved glucose uptake in an apolipoprotein AI treated mouse model of diabetes. Diabetologia, 59(9), 1977-1984. doi:10.1007/s00125-016-3993-5
Abstract: Type 2 diabetes is characterised by decreased HDL levels, as well as the level of apolipoprotein A-I (apoA-I), the main apolipoprotein of HDLs. Pharmacological elevation of HDL and apoA-I levels is associated with improved glycaemic control in patients with type 2 diabetes. This is partly due to improved glucose uptake in skeletal muscle.© 2016 Springer Nature
Gov't Doc #: 8698
ISSN: 1432-0428
Appears in Collections:Journal Articles

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