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ANSTO Publications Online

Welcome to the ANSTO Institutional Repository known as APO.

The APO database has been migrated to version 8.3. The functionality has changed, but the content remains the same.

ANSTO Publications Online is a digital repository for publications authored by ANSTO staff since 2007. The Repository also contains ANSTO Publications, such as Reports and Promotional Material. ANSTO publications prior to 2007 continue to be added progressively as they are in identified in the library. ANSTO authors can be identified under a single point of entry within the database. The citation is as it appears on the item, even with incorrect spelling, which is marked by (sic) or with additional notes in the description field.

If items are only held in hardcopy in the ANSTO Library collection notes are being added to the item to identify the Dewey Call number: as DDC followed by the number.

APO will be integrated with the Research Information System which is currently being implemented at ANSTO. The flow on effect will be permission to publish, which should allow pre-prints and post prints to be added where content is locked behind a paywall. To determine which version can be added to APO authors should check Sherpa Romeo. ANSTO research is increasingly being published in open access due mainly to the Council of Australian University Librarians read and publish agreements, and some direct publisher agreements with our organisation. In addition, open access items are also facilitated through collaboration and open access agreements with overseas authors such as Plan S.

ANSTO authors are encouraged to use a CC-BY licence when publishing open access. Statistics have been returned to the database and are now visible to users to show item usage and where this usage is coming from.

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    Proceedings to the 58th Annual Conference of the Particle Therapy Cooperative Group (PTCOG58)
    (Elsevier, 2020-03) Particle Therapy Cooperative Group (PTCOG)
    No Abstract
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    Ionic liquid adsorption at the silica–oil interface revealed by neutron reflectometry
    (American Chemical Society, 2018-09-18) Cooper, PK; Li, H; Yepuri, NR; Nelson, A; Webber, GB; Le Brun, AP; Darwish, TA; Warr, GG; Atkin, R
    Previous nanotribology measurements demonstrated that 2 mol % of the oil-miscible ionic liquid (IL) trihexyltetradecyl­(phosphonium) bis­(2,4,4-trimethylpentyl)­phosphinate (P6,6,6,14 ( i C8)2PO2) diluted in octane lubricated as effectively as pure IL. However, until now the structure and composition of the lubricating adsorbed layer, which is critical for lubrication, was unknown. Here, the unconfined structure of the IL adsorbed layer at the oil–silica interface has been studied using neutron reflectometry. Multiple neutron contrasts revealed an 8 Å thick adsorbed layer, even at 60 and 80 °C. The ratio of cations and anions in the layer was investigated by synthesizing the IL with deuterated cations and measuring its reflectivity at the oil–silica interface. At 60 °C the layer was composed of 48 ± 6 mol % P6,6,6,14 + cations, 24 ± 2 mol % ( i C8)2PO2 – anions, and 28 ± 8 mol % octane, while at 80 °C the composition was 50 ± 2 mol % P6,6,6,14 +, 28 ± 2 mol % ( i C8)2PO2 – anions, and 22 ± 2 mol % octane. These results reinforce the importance of the judicious selection of IL cations and anions for charged surfaces and support their use in high-temperature applications. © 2018 American Chemical Society.
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    Daptomycin-loaded nanocarriers facilitate synergistic killing of methicillin-resistant staphylococcus aureus via lipid-mediated interactions and targeting
    (Oxford University Press (OUP), 2026-01-15) Jiang, JH; Lim, CX; Lai, XF; Kostoulias, XP; Morris, FC; Le Brun, AP; Wu, CM; Yepuri, NR; Shen, HH; Peleg, AY
    Preservation and augmentation of existing antimicrobials is crucial in combating antimicrobial resistance. Gram-positive bacteria, exemplified by Staphylococcus aureus, are among the most common human bacterial pathogens, with methicillin-resistant S. aureus (MRSA) now established globally. Daptomycin is a last-line anti-staphylococcal antimicrobial that uniquely targets the bacterial membrane with bactericidal effects. Here, we developed lipid-based nanoparticles, namely cubosomes, to encapsulate daptomycin for targeted delivery via lipid-mediated interactions. Daptomycin-loaded cubosomes synergistically killed 14 clinical MRSA isolates in vitro compared with daptomycin or cubosomes alone. This synergy between daptomycin and cubosome was mediated by cubosomes docking on the S. aureus cell surface, releasing daptomycin for membrane extraction and penetration, followed by lipid cubosome infusion into S. aureus membranes. Using a murine septicemia model, daptomycin-loaded cubosomes significantly reduced the organ bacterial burden of MRSA. Together, these data showed that multifunctional lipid nanocarriers can potentiate the bactericidal activity of daptomycin using a membrane-targeted trojan-horse-like mechanism. © The Author(s) 2025. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence.
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    A quantitative review of slurries for hydrogen storage – slush hydrogen, and metal and chemical hydrides in carrier liquids
    (Elsevier, 2022-06-15) Lamb, KE; Webb, CJ
    Methods of storing hydrogen for energy applications have been widely discussed, both across time and by people from various organisations and backgrounds. Recently, interest in hydrogen storage has developed for space exploration, for both terrestrial and extra-terrestrial applications, and more recently by politicians and business leaders for displacing carbon-intensive fuels. Hydrogen storage options range from solid to gas phases, with several detailed reviews focussing on metal hydrides such as alkali-earth alloys, chemical hydrides such as ammonia, and liquid organic carriers available. An overlooked part of the literature has been hydrogen storage in slurries, where each method of storage has unique advantages, challenges, and stages of research and development. Here, we focus on reviewing the literature on slush hydrogen and slurries of metal and chemical hydrides. © 2022 Published by Elsevier B.V.
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    Variations in Mid‐ to Late Holocene nitrogen supply to Northern Great Barrier Reef Halimeda macroalgal bioherms
    (American Geophysical Union, 2021-01-18) McNeil, M; Nothdurft, L; Erler, DV; Hua, Q; Webster, JM
    Abstract The northern Great Barrier Reef (GBR) Halimeda bioherms have accumulated on the outer continental shelf from calcium carbonate algal sediments over the past ∼10,000 years and cover >6,000 km 2 of shelf area. As such, Halimeda bioherms play a key role in the shallow marine carbon cycle over millennial timescales. The main source of nitrogen (N) to these bioherms is thought to be westward transport of upwelled NO 3 ‐ ‐rich water from the Coral Sea. However, the primary N source has not been traced geochemically, and we have no understanding of any temporal variation. Here, we reconstruct patterns of N supply to Halimeda bioherms in the GBR since the mid‐Holocene using the 15 N/ 14 N ratio of skeletal‐bound organic N (δ 15 N‐skeletal organic material [SOM]) in modern and fossil Halimeda sediment cores. Average Halimeda skeletal δ 15 N‐SOM was 6.28 ± 0.26‰, consistent with δ 15 N‐NO 3 ‐ from western tropical South Pacific (WTSP) thermocline waters. Thus, geochemically validating shelf‐break upwelling of an oceanic N source that regulates bioherm spatial distribution. Halimeda δ 15 N‐SOM decreased by 1‰–2‰ from 5,000 to 2,000 cal. yr BP, reaching a minima of 5.5‰ that persisted for almost 1,000 years. The Halimeda δ 15 N‐SOM variation reflects mid‐ to late Holocene changes in regional climate and intensified El Niño activity that likely facilitated elevated N 2 fixation in the WTSP, thereby lowering thermocline δ 15 N‐NO 3 ‐ . Thus, Halimeda skeletal material provides a valuable high‐resolution geochemical archive of past oceanographic and climatic processes over centennial to millennial timescales, complementing existing paleoclimate proxy records. Key Points Well‐preserved fossil Halimeda is a valuable geochemical proxy archive of millennial‐scale oceanographic and climatic processes. Nitrogen (N) supply to Halimeda bioherms originates from western tropical South Pacific thermocline waters since at least the past 5,000 years. Halimeda 15 N signature records a 1‰–2‰ change in δ 15 N‐skeletal organic material (SOM) concurrent with regional climate variation and the El Niño Southern Oscillation. © 2021. American Geophysical Union.